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Therapeutic Drug Monitoring-Guided Adjuvant Tamoxifen Dosing in Patients with Early Breast Cancer: A Cost-Effectiveness Analysis from the Prospective TOTAM Trial
BACKGROUND AND OBJECTIVES: Endoxifen is the active metabolite of tamoxifen, and a minimal plasma concentration of 16 nM has been suggested as a threshold above which it is effective in reducing the risk of breast cancer recurrence. The aim of the current analysis was to investigate the cost-effectiv...
Autores principales: | Braal, C. Louwrens, Kleijburg, Anne, Jager, Agnes, Koolen, Stijn L. W., Mathijssen, Ron H. J., Corro Ramos, Isaac, Wetzelaer, Pim, Uyl-de Groot, Carin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844136/ https://www.ncbi.nlm.nih.gov/pubmed/35020170 http://dx.doi.org/10.1007/s40261-021-01114-6 |
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