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Cross-reactive, natural IgG recognizing L. major promote parasite internalization by dendritic cells and promote protective immunity
ABSTRACT: In cutaneous leishmaniasis, infection of dendritic cells (DC) is essential for generation of T cell-dependent protective immunity. DC acquires Leishmania major through Fc receptor (FcR)-mediated uptake of complexes comprising antibodies bound to parasites. We now assessed the development o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844169/ https://www.ncbi.nlm.nih.gov/pubmed/34604942 http://dx.doi.org/10.1007/s00109-021-02137-4 |