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Cross-reactive, natural IgG recognizing L. major promote parasite internalization by dendritic cells and promote protective immunity

ABSTRACT: In cutaneous leishmaniasis, infection of dendritic cells (DC) is essential for generation of T cell-dependent protective immunity. DC acquires Leishmania major through Fc receptor (FcR)-mediated uptake of complexes comprising antibodies bound to parasites. We now assessed the development o...

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Detalles Bibliográficos
Autores principales: Dermicik, Filiz, Lopez Kostka, Susanna, Tenzer, Stefan, Waisman, Ari, Von Stebut, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844169/
https://www.ncbi.nlm.nih.gov/pubmed/34604942
http://dx.doi.org/10.1007/s00109-021-02137-4