Cargando…

Safety, Pharmacokinetics and Pharmacodynamics of DS-1040, in Combination with Thrombectomy, in Japanese Patients with Acute Ischemic Stroke

BACKGROUND AND OBJECTIVES: DS-1040 is a novel inhibitor of the activated form of thrombin-activatable fibrinolysis inhibitor that may have therapeutic potential in thromboembolic diseases, such as acute ischemic stroke (AIS) or pulmonary embolism. We undertook a Phase I clinical trial to investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sakai, Nobuyuki, Takeuchi, Masataka, Imamura, Hirotoshi, Shimamura, Norihito, Yoshimura, Shinichi, Naito, Hiromichi, Kimura, Naoto, Masuo, Osamu, Hirotsune, Nobuyuki, Morita, Kenichi, Toyoda, Kazunori, Yamagami, Hiroshi, Ishihara, Hideyuki, Nakatsu, Takafumi, Miyoshi, Naoki, Suda, Miharu, Fujimoto, Shigeru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844171/ https://www.ncbi.nlm.nih.gov/pubmed/35061236 http://dx.doi.org/10.1007/s40261-021-01112-8

Ejemplares similares

Endovascular Treatment of Acute Stroke with Major Vessel Occlusion before Approval of Mechanical Thrombectomy Devices in Japan: Japanese Registry of Neuroendovascular Therapy (JR-NET) and JR-NET 2
por: HAYAKAWA, Mikito, et al.
Publicado: (2014)

Effect of Statin Administration After Onset of Acute Ischemic Stroke With Large Vessel Occlusion: Insights From RESCUE‐Japan Registry 2
por: Uchida, Kazutaka, et al.
Publicado: (2020)

1040 ejercicios de fuerza explosiva
por: Rius, Joan (Rius Sant)

Efficacy and Safety of REVIVE SE Thrombectomy Device for Acute Ischemic Stroke: River JAPAN (Reperfuse Ischemic Vessels with Endovascular Recanalization Device in Japan)
por: SAKAI, Nobuyuki, et al.
Publicado: (2018)

P1040: FACTORS ASSOCIATED WITH THROMBOSIS IN MYELOFIBROSIS
por: Bankar, Aniket, et al.
Publicado: (2023)

A Child with Paradoxical Cerebral Embolism in Whom Mechanical Thrombectomy Led to a Favorable Outcome
por: Soutome, Yuta, et al.
Publicado: (2020)

Wiley Tax Preparer: A Guide to Form 1040
por: The Tax Institute at H&R Block
Publicado: (2013)

Helicobacter cinaedi-infected chronic subdural hematoma mimicking an expanding hematoma: A case report
por: Akiyama, Tomoaki, et al.
Publicado: (2021)

Safety of Early Administration of Apixaban on Clinical Outcomes in Patients with Acute Large Vessel Occlusion
por: Yoshimura, Shinichi, et al.
Publicado: (2020)

Correction to: Safety of Early Administration of Apixaban on Clinical Outcomes in Patients with Acute Large Vessel Occlusion
por: Yoshimura, Shinichi, et al.
Publicado: (2020)

Variant analysis of 1,040 SARS-CoV-2 genomes
por: Rouchka, Eric C., et al.
Publicado: (2020)

Trends in Endovascular Reperfusion Therapy for Acute Stroke after Introduction of Mechanical Thrombectomy Devices: Japanese Registry of NeuroEndovascular Therapy (JR-NET)3
por: HAYAKAWA, Mikito, et al.
Publicado: (2020)

Book Review: Pharmacokinetic and Pharmacodynamic Data Analysis ‐ Concepts and Applications, 5th Edition, by Johan Gabrielsson and Daniel Weiner Apotekarsocieteten, 2016 1,040 pp, hardcover ISBN: 9789198299106
por: Krekels, Elke H.J.
Publicado: (2016)

Metabolic conversion of CI-1040 turns a cellular MEK-inhibitor into an antibacterial compound
por: Bruchhagen, Christin, et al.
Publicado: (2018)

Angioplasty and Stenting for Intracranial Stenosis
por: IZUMI, Takashi, et al.
Publicado: (2014)

Endovascular Treatment for Vasospasm after Aneurysmal Subarachnoid Hemorrhage Based on Data of JR-NET3
por: IMAMURA, Hirotoshi, et al.
Publicado: (2018)

Stent-assisted Coil Embolization to Treat Extracranial Carotid Artery Aneurysm 13 Years after Endarterectomy: A Case Report
por: Haruma, Jun, et al.
Publicado: (2019)

Correlation of Middle Cerebral Artery Tortuosity with Successful Recanalization Using the Merci Retrieval System with or without Adjunctive Treatments
por: YAMAMOTO, Shiro, et al.
Publicado: (2014)

Health status in 1040 adults with disorders of sex development (DSD): a European multicenter study
por: Falhammar, Henrik, et al.
Publicado: (2018)

Endovascular Treatment of Aneurysmal Subarachnoid Hemorrhage in Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2
por: IMAMURA, Hirotoshi, et al.
Publicado: (2014)

Postoperative Subdural Air Collection Is a Risk Factor for Chronic Subdural Hematoma after Surgical Clipping of Cerebral Aneurysms
por: KAWABATA, Shuhei, et al.
Publicado: (2018)

Endovascular Therapy for Intracranial Artery Stenosis: Results from the Japanese Registry of Neuroendovascular Therapy (JR-NET)3
por: IZUMI, Takashi, et al.
Publicado: (2020)

Postcoiling syndrome including headache and fever after endovascular cerebral aneurysmal coil embolization: A narrative review
por: Okuma, Yu, et al.
Publicado: (2023)

Antibacterial activity of selected commercial products for mouth washing and disinfection, assessed in accordance with PN-EN 1040
por: Tyski, Stefan, et al.
Publicado: (2013)

Modification of Serine 1040 of SIBRI1 Increases Fruit Yield by Enhancing Tolerance to Heat Stress in Tomato
por: Wang, Shufen, et al.
Publicado: (2020)

Discrepancy between Cytology and Histology in Cervical Cancer Screening: a Multicenter Retrospective Study (KGOG 1040)
por: Ouh, Yung-Taek, et al.
Publicado: (2021)

SG-APSIC1040: Implementing a quality-improvement approach to surgical-site infection prevention in the Philippines
por: Abustan, Anthony, et al.
Publicado: (2023)

Optimal dilution of contrast medium for quantitating parenchymal blood volume using a flat-panel detector
por: Kuriyama, Takumi, et al.
Publicado: (2017)

Reversible Cerebral Vasoconstriction Syndrome in Early Pregnancy Treated with Endovascular Therapy
por: Fujiwara, Satoru, et al.
Publicado: (2020)

MD, run 1040 and 1046, Development of a new program for automatic vertical beam steering to optimise luminosity
por: Hémery, J Y, et al.
Publicado: (1979)

Combination of Rapamycin, CI-1040, and 17-AAG Inhibits Metastatic Capacity of Prostate Cancer via Slug Inhibition
por: Ding, Guanxiong, et al.
Publicado: (2013)

1040. Comparative Characteristics of Patients With Pseudomonas Bacteremia Receiving Intravenous Only vs. Intravenous Followed by Oral Therapy
por: Vu, Trung, et al.
Publicado: (2018)

Efficacy and Safety of Lactobacillus reuteri CCFM1040 in Allergic Rhinitis and Asthma: A Randomized, Placebo-Controlled Trial
por: Li, Lingzhi, et al.
Publicado: (2022)

Impaired Decision-Making Capacity in the Elderly King David (c. 1040–970 BCE): Was Hypothyroidism the Underlying Cause?
por: Mendlowicz, Mauro V., et al.
Publicado: (2023)

Pharmacokinetics of Temozolomide in a Patient With Glioblastoma Undergoing Hemodialysis: A Short Communication
por: Tanaka, Fumiaki, et al.
Publicado: (2023)

Impact of COVID-19 on the Volume of Acute Stroke Admissions: A Nationwide Survey in Japan
por: YOSHIMOTO, Takeshi, et al.
Publicado: (2022)

Convulsive-like symptoms as initial indications of basilar artery occlusion: A case series study
por: Inui, Ryoma, et al.
Publicado: (2022)

Rapid Response System for In-Hospital Large Vessel Occlusion: A Case-Control Study
por: Fujiwara, Satoru, et al.
Publicado: (2021)

Bilateral Chronic Subdural Hematoma is Associated with Rapid Progression and Poor Clinical Outcome
por: AGAWA, Yuji, et al.
Publicado: (2016)

Recurrence of a Refractory Chronic Subdural Hematoma after Middle Meningeal Artery Embolization That Required Craniotomy
por: Chihara, Hideo, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_h10h5ejf6ddc5amilqjk24fgf5