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Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction
We describe a case of a severe but rare adverse reaction to recombinant varicella-zoster virus (VZV) vaccination: a 67-year-old female admitted with gradual onset of shortness of breath, hypoxia, and fever following VZV vaccination. The clinical picture and radiologic presentation mimicked COVID-19...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844295/ https://www.ncbi.nlm.nih.gov/pubmed/35186513 http://dx.doi.org/10.7759/cureus.21181 |
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author | Khawaja, Imran Al-Ourani, Mohammed |
author_facet | Khawaja, Imran Al-Ourani, Mohammed |
author_sort | Khawaja, Imran |
collection | PubMed |
description | We describe a case of a severe but rare adverse reaction to recombinant varicella-zoster virus (VZV) vaccination: a 67-year-old female admitted with gradual onset of shortness of breath, hypoxia, and fever following VZV vaccination. The clinical picture and radiologic presentation mimicked COVID-19 pneumonia. However, repeated testing for COVID-19 by PCR was negative. A diagnosis of organizing pneumonia was made on transbronchial biopsies. The patient responded well to steroids and improved both clinically and radiographically. This case illustrates not only a rare and unreported complication from vaccination but also raises the awareness during the COVID-19 pandemic that other etiologies can mimic COVID-19 pneumonia. Physicians should be aware of other diagnoses that can mimic COVID-19 infection. |
format | Online Article Text |
id | pubmed-8844295 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88442952022-02-17 Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction Khawaja, Imran Al-Ourani, Mohammed Cureus Radiology We describe a case of a severe but rare adverse reaction to recombinant varicella-zoster virus (VZV) vaccination: a 67-year-old female admitted with gradual onset of shortness of breath, hypoxia, and fever following VZV vaccination. The clinical picture and radiologic presentation mimicked COVID-19 pneumonia. However, repeated testing for COVID-19 by PCR was negative. A diagnosis of organizing pneumonia was made on transbronchial biopsies. The patient responded well to steroids and improved both clinically and radiographically. This case illustrates not only a rare and unreported complication from vaccination but also raises the awareness during the COVID-19 pandemic that other etiologies can mimic COVID-19 pneumonia. Physicians should be aware of other diagnoses that can mimic COVID-19 infection. Cureus 2022-01-12 /pmc/articles/PMC8844295/ /pubmed/35186513 http://dx.doi.org/10.7759/cureus.21181 Text en Copyright © 2022, Khawaja et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Radiology Khawaja, Imran Al-Ourani, Mohammed Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction |
title | Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction |
title_full | Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction |
title_fullStr | Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction |
title_full_unstemmed | Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction |
title_short | Organizing Pneumonia Following Recombinant Zoster Vaccination: A Rare Adverse Reaction |
title_sort | organizing pneumonia following recombinant zoster vaccination: a rare adverse reaction |
topic | Radiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844295/ https://www.ncbi.nlm.nih.gov/pubmed/35186513 http://dx.doi.org/10.7759/cureus.21181 |
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