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Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind

Drug-induced liver injury (DILI) is a rare condition with a high burden of morbidity and risk of severe complications that may even require liver transplantation to survive. There are no pathognomonic diagnostic tests for this condition, thus being a challenge it is considered a diagnosis of exclusi...

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Detalles Bibliográficos
Autores principales: Blanquicett, Alejandro, Martinez-Ávila, Maria Cristina, Mondol, Zulay, Imbeth Acosta, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844318/
https://www.ncbi.nlm.nih.gov/pubmed/35186522
http://dx.doi.org/10.7759/cureus.21220
Descripción
Sumario:Drug-induced liver injury (DILI) is a rare condition with a high burden of morbidity and risk of severe complications that may even require liver transplantation to survive. There are no pathognomonic diagnostic tests for this condition, thus being a challenge it is considered a diagnosis of exclusion. We present the case of a patient who, after starting intramuscular contraceptives, presented with acute alteration of liver function that requires the ruling out of multiple pathologies that could be the cause of the biochemical findings. With the pharmacological suspension and initiation of support measures, full recovery was achieved.