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Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind

Drug-induced liver injury (DILI) is a rare condition with a high burden of morbidity and risk of severe complications that may even require liver transplantation to survive. There are no pathognomonic diagnostic tests for this condition, thus being a challenge it is considered a diagnosis of exclusi...

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Autores principales: Blanquicett, Alejandro, Martinez-Ávila, Maria Cristina, Mondol, Zulay, Imbeth Acosta, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844318/
https://www.ncbi.nlm.nih.gov/pubmed/35186522
http://dx.doi.org/10.7759/cureus.21220
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author Blanquicett, Alejandro
Martinez-Ávila, Maria Cristina
Mondol, Zulay
Imbeth Acosta, Pedro
author_facet Blanquicett, Alejandro
Martinez-Ávila, Maria Cristina
Mondol, Zulay
Imbeth Acosta, Pedro
author_sort Blanquicett, Alejandro
collection PubMed
description Drug-induced liver injury (DILI) is a rare condition with a high burden of morbidity and risk of severe complications that may even require liver transplantation to survive. There are no pathognomonic diagnostic tests for this condition, thus being a challenge it is considered a diagnosis of exclusion. We present the case of a patient who, after starting intramuscular contraceptives, presented with acute alteration of liver function that requires the ruling out of multiple pathologies that could be the cause of the biochemical findings. With the pharmacological suspension and initiation of support measures, full recovery was achieved.
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spelling pubmed-88443182022-02-17 Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind Blanquicett, Alejandro Martinez-Ávila, Maria Cristina Mondol, Zulay Imbeth Acosta, Pedro Cureus Emergency Medicine Drug-induced liver injury (DILI) is a rare condition with a high burden of morbidity and risk of severe complications that may even require liver transplantation to survive. There are no pathognomonic diagnostic tests for this condition, thus being a challenge it is considered a diagnosis of exclusion. We present the case of a patient who, after starting intramuscular contraceptives, presented with acute alteration of liver function that requires the ruling out of multiple pathologies that could be the cause of the biochemical findings. With the pharmacological suspension and initiation of support measures, full recovery was achieved. Cureus 2022-01-13 /pmc/articles/PMC8844318/ /pubmed/35186522 http://dx.doi.org/10.7759/cureus.21220 Text en Copyright © 2022, Blanquicett et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Blanquicett, Alejandro
Martinez-Ávila, Maria Cristina
Mondol, Zulay
Imbeth Acosta, Pedro
Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind
title Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind
title_full Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind
title_fullStr Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind
title_full_unstemmed Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind
title_short Toxic Hepatitis Associated With the Use of Contraceptives: A Diagnosis to Bear in Mind
title_sort toxic hepatitis associated with the use of contraceptives: a diagnosis to bear in mind
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844318/
https://www.ncbi.nlm.nih.gov/pubmed/35186522
http://dx.doi.org/10.7759/cureus.21220
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