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Kidney-Related Outcome in Cardiorenal Syndrome Type 3

METHODS: A single-center, retrospective and observational trial. All subjects with positive AKI alert, treated at the University Hospital Brandenburg between January and December 2019, were evaluated. Definition of CRS type 3 was according to predefined criteria. The three endpoint categories were i...

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Autores principales: Drubel, Kim, Marahrens, Benedikt, Ritter, Oliver, Patschan, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844349/
https://www.ncbi.nlm.nih.gov/pubmed/35178254
http://dx.doi.org/10.1155/2022/4895434
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author Drubel, Kim
Marahrens, Benedikt
Ritter, Oliver
Patschan, Daniel
author_facet Drubel, Kim
Marahrens, Benedikt
Ritter, Oliver
Patschan, Daniel
author_sort Drubel, Kim
collection PubMed
description METHODS: A single-center, retrospective and observational trial. All subjects with positive AKI alert, treated at the University Hospital Brandenburg between January and December 2019, were evaluated. Definition of CRS type 3 was according to predefined criteria. The three endpoint categories were in-hospital death, dialysis, and recovery of kidney function. RESULTS: . A total number of 1,334 AKI alerts were screened. Finally, 95 subjects received the diagnosis CRS type 3. The survival rates were 47.1% (females) and 43.6% (males). 46.8% of affected females and 33.3% of the males required dialysis therapy. Complete recovery at the time of discharge occurred in 35.8%, and no recovery at all was found in 54.7%. CONCLUSIONS: . All three predefined study endpoints, the mortality, the prevalence of dialysis, and the percentage of subjects without recovery of kidney function, were notably high. Therefore, AKI patients with imminent or established cardiac complications require the highest attention of nephrologists in charge.
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spelling pubmed-88443492022-02-16 Kidney-Related Outcome in Cardiorenal Syndrome Type 3 Drubel, Kim Marahrens, Benedikt Ritter, Oliver Patschan, Daniel Int J Nephrol Research Article METHODS: A single-center, retrospective and observational trial. All subjects with positive AKI alert, treated at the University Hospital Brandenburg between January and December 2019, were evaluated. Definition of CRS type 3 was according to predefined criteria. The three endpoint categories were in-hospital death, dialysis, and recovery of kidney function. RESULTS: . A total number of 1,334 AKI alerts were screened. Finally, 95 subjects received the diagnosis CRS type 3. The survival rates were 47.1% (females) and 43.6% (males). 46.8% of affected females and 33.3% of the males required dialysis therapy. Complete recovery at the time of discharge occurred in 35.8%, and no recovery at all was found in 54.7%. CONCLUSIONS: . All three predefined study endpoints, the mortality, the prevalence of dialysis, and the percentage of subjects without recovery of kidney function, were notably high. Therefore, AKI patients with imminent or established cardiac complications require the highest attention of nephrologists in charge. Hindawi 2022-02-07 /pmc/articles/PMC8844349/ /pubmed/35178254 http://dx.doi.org/10.1155/2022/4895434 Text en Copyright © 2022 Kim Drubel et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Drubel, Kim
Marahrens, Benedikt
Ritter, Oliver
Patschan, Daniel
Kidney-Related Outcome in Cardiorenal Syndrome Type 3
title Kidney-Related Outcome in Cardiorenal Syndrome Type 3
title_full Kidney-Related Outcome in Cardiorenal Syndrome Type 3
title_fullStr Kidney-Related Outcome in Cardiorenal Syndrome Type 3
title_full_unstemmed Kidney-Related Outcome in Cardiorenal Syndrome Type 3
title_short Kidney-Related Outcome in Cardiorenal Syndrome Type 3
title_sort kidney-related outcome in cardiorenal syndrome type 3
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844349/
https://www.ncbi.nlm.nih.gov/pubmed/35178254
http://dx.doi.org/10.1155/2022/4895434
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