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Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements

Vitamin D supplementation is routinely introduced in infants, according to medical guidelines. However, vitamin D overdose can result in life-threatening hypercalcemia. We report the case of a 3-month-old infant who suffered from severe hypercalcemia. Upon detailed questioning of the parents, a vita...

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Autores principales: Gérard, Alexandre O., Fresse, Audrey, Gast, Myriam, Merino, Diane, Gourdan, Pierre, Laurain, Audrey, Margaritis, Irène, Gauci, Pierre-Alexis, Huret, Fanny, Parassol, Nadège, Rocher, Fanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844365/
https://www.ncbi.nlm.nih.gov/pubmed/35178365
http://dx.doi.org/10.3389/fped.2022.816965
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author Gérard, Alexandre O.
Fresse, Audrey
Gast, Myriam
Merino, Diane
Gourdan, Pierre
Laurain, Audrey
Margaritis, Irène
Gauci, Pierre-Alexis
Huret, Fanny
Parassol, Nadège
Rocher, Fanny
author_facet Gérard, Alexandre O.
Fresse, Audrey
Gast, Myriam
Merino, Diane
Gourdan, Pierre
Laurain, Audrey
Margaritis, Irène
Gauci, Pierre-Alexis
Huret, Fanny
Parassol, Nadège
Rocher, Fanny
author_sort Gérard, Alexandre O.
collection PubMed
description Vitamin D supplementation is routinely introduced in infants, according to medical guidelines. However, vitamin D overdose can result in life-threatening hypercalcemia. We report the case of a 3-month-old infant who suffered from severe hypercalcemia. Upon detailed questioning of the parents, a vitamin D administration error has been identified. Indeed, the parents had followed the advice of their midwife. They substituted the prescribed medicinal vitamin D by a dietary supplement, different in concentration and dosing, without performing the dose conversion needed. In fact, many different medications and dietary supplements with vitamin D exist, offering various concentrations and units of measurement. This case highlights the pivotal role of therapeutic education. Broadly, there is a need for harmonization of the regulation and labeling of dietary supplements and medications containing vitamin D.
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spelling pubmed-88443652022-02-16 Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements Gérard, Alexandre O. Fresse, Audrey Gast, Myriam Merino, Diane Gourdan, Pierre Laurain, Audrey Margaritis, Irène Gauci, Pierre-Alexis Huret, Fanny Parassol, Nadège Rocher, Fanny Front Pediatr Pediatrics Vitamin D supplementation is routinely introduced in infants, according to medical guidelines. However, vitamin D overdose can result in life-threatening hypercalcemia. We report the case of a 3-month-old infant who suffered from severe hypercalcemia. Upon detailed questioning of the parents, a vitamin D administration error has been identified. Indeed, the parents had followed the advice of their midwife. They substituted the prescribed medicinal vitamin D by a dietary supplement, different in concentration and dosing, without performing the dose conversion needed. In fact, many different medications and dietary supplements with vitamin D exist, offering various concentrations and units of measurement. This case highlights the pivotal role of therapeutic education. Broadly, there is a need for harmonization of the regulation and labeling of dietary supplements and medications containing vitamin D. Frontiers Media S.A. 2022-02-01 /pmc/articles/PMC8844365/ /pubmed/35178365 http://dx.doi.org/10.3389/fped.2022.816965 Text en Copyright © 2022 Gérard, Fresse, Gast, Merino, Gourdan, Laurain, Margaritis, Gauci, Huret, Parassol and Rocher. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Gérard, Alexandre O.
Fresse, Audrey
Gast, Myriam
Merino, Diane
Gourdan, Pierre
Laurain, Audrey
Margaritis, Irène
Gauci, Pierre-Alexis
Huret, Fanny
Parassol, Nadège
Rocher, Fanny
Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements
title Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements
title_full Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements
title_fullStr Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements
title_full_unstemmed Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements
title_short Case Report: Severe Hypercalcemia Following Vitamin D Intoxication in an Infant, the Underestimated Danger of Dietary Supplements
title_sort case report: severe hypercalcemia following vitamin d intoxication in an infant, the underestimated danger of dietary supplements
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844365/
https://www.ncbi.nlm.nih.gov/pubmed/35178365
http://dx.doi.org/10.3389/fped.2022.816965
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