Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis

Regions of low oxygen (hypoxia) are found in >50% of breast tumours, most frequently in the more aggressive triple negative breast cancer subtype (TNBC). Metastasis is the cause of 90% of breast cancer patient deaths. Regions of tumour hypoxia tend to be more acidic and both hypoxia and acidosis...

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Detalles Bibliográficos
Autores principales: Carroll, Christopher Paul, Bolland, Hannah, Vancauwenberghe, Eric, Collier, Pamela, Ritchie, Alison A., Clarke, Philip A., Grabowska, Anna M., Harris, Adrian L, McIntyre, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844412/
https://www.ncbi.nlm.nih.gov/pubmed/35150959
http://dx.doi.org/10.1016/j.neo.2022.01.003

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