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skater: an R package for SNP-based kinship analysis, testing, and evaluation
Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionali...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844523/ https://www.ncbi.nlm.nih.gov/pubmed/35222994 http://dx.doi.org/10.12688/f1000research.76004.1 |
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author | Turner, Stephen D. Nagraj, V.P. Scholz, Matthew Jessa, Shakeel Acevedo, Carlos Ge, Jianye Woerner, August E. Budowle, Bruce |
author_facet | Turner, Stephen D. Nagraj, V.P. Scholz, Matthew Jessa, Shakeel Acevedo, Carlos Ge, Jianye Woerner, August E. Budowle, Bruce |
author_sort | Turner, Stephen D. |
collection | PubMed |
description | Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionality is needed. Results: Here we present the skater R package for SNP-based kinship analysis, testing, and evaluation with R. The skater package contains a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data. Availability: The skater package is implemented as an R package and is released under the MIT license at https://github.com/signaturescience/skater. Documentation is available at https://signaturescience.github.io/skater. |
format | Online Article Text |
id | pubmed-8844523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-88445232022-02-24 skater: an R package for SNP-based kinship analysis, testing, and evaluation Turner, Stephen D. Nagraj, V.P. Scholz, Matthew Jessa, Shakeel Acevedo, Carlos Ge, Jianye Woerner, August E. Budowle, Bruce F1000Res Software Tool Article Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionality is needed. Results: Here we present the skater R package for SNP-based kinship analysis, testing, and evaluation with R. The skater package contains a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data. Availability: The skater package is implemented as an R package and is released under the MIT license at https://github.com/signaturescience/skater. Documentation is available at https://signaturescience.github.io/skater. F1000 Research Limited 2022-01-07 /pmc/articles/PMC8844523/ /pubmed/35222994 http://dx.doi.org/10.12688/f1000research.76004.1 Text en Copyright: © 2022 Turner SD et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Software Tool Article Turner, Stephen D. Nagraj, V.P. Scholz, Matthew Jessa, Shakeel Acevedo, Carlos Ge, Jianye Woerner, August E. Budowle, Bruce skater: an R package for SNP-based kinship analysis, testing, and evaluation |
title | skater: an R package for SNP-based kinship analysis, testing, and evaluation |
title_full | skater: an R package for SNP-based kinship analysis, testing, and evaluation |
title_fullStr | skater: an R package for SNP-based kinship analysis, testing, and evaluation |
title_full_unstemmed | skater: an R package for SNP-based kinship analysis, testing, and evaluation |
title_short | skater: an R package for SNP-based kinship analysis, testing, and evaluation |
title_sort | skater: an r package for snp-based kinship analysis, testing, and evaluation |
topic | Software Tool Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844523/ https://www.ncbi.nlm.nih.gov/pubmed/35222994 http://dx.doi.org/10.12688/f1000research.76004.1 |
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