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skater: an R package for SNP-based kinship analysis, testing, and evaluation

Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionali...

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Autores principales: Turner, Stephen D., Nagraj, V.P., Scholz, Matthew, Jessa, Shakeel, Acevedo, Carlos, Ge, Jianye, Woerner, August E., Budowle, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844523/
https://www.ncbi.nlm.nih.gov/pubmed/35222994
http://dx.doi.org/10.12688/f1000research.76004.1
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author Turner, Stephen D.
Nagraj, V.P.
Scholz, Matthew
Jessa, Shakeel
Acevedo, Carlos
Ge, Jianye
Woerner, August E.
Budowle, Bruce
author_facet Turner, Stephen D.
Nagraj, V.P.
Scholz, Matthew
Jessa, Shakeel
Acevedo, Carlos
Ge, Jianye
Woerner, August E.
Budowle, Bruce
author_sort Turner, Stephen D.
collection PubMed
description Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionality is needed. Results: Here we present the skater R package for SNP-based kinship analysis, testing, and evaluation with R. The skater package contains a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data. Availability: The skater package is implemented as an R package and is released under the MIT license at https://github.com/signaturescience/skater. Documentation is available at https://signaturescience.github.io/skater.
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spelling pubmed-88445232022-02-24 skater: an R package for SNP-based kinship analysis, testing, and evaluation Turner, Stephen D. Nagraj, V.P. Scholz, Matthew Jessa, Shakeel Acevedo, Carlos Ge, Jianye Woerner, August E. Budowle, Bruce F1000Res Software Tool Article Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionality is needed. Results: Here we present the skater R package for SNP-based kinship analysis, testing, and evaluation with R. The skater package contains a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data. Availability: The skater package is implemented as an R package and is released under the MIT license at https://github.com/signaturescience/skater. Documentation is available at https://signaturescience.github.io/skater. F1000 Research Limited 2022-01-07 /pmc/articles/PMC8844523/ /pubmed/35222994 http://dx.doi.org/10.12688/f1000research.76004.1 Text en Copyright: © 2022 Turner SD et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software Tool Article
Turner, Stephen D.
Nagraj, V.P.
Scholz, Matthew
Jessa, Shakeel
Acevedo, Carlos
Ge, Jianye
Woerner, August E.
Budowle, Bruce
skater: an R package for SNP-based kinship analysis, testing, and evaluation
title skater: an R package for SNP-based kinship analysis, testing, and evaluation
title_full skater: an R package for SNP-based kinship analysis, testing, and evaluation
title_fullStr skater: an R package for SNP-based kinship analysis, testing, and evaluation
title_full_unstemmed skater: an R package for SNP-based kinship analysis, testing, and evaluation
title_short skater: an R package for SNP-based kinship analysis, testing, and evaluation
title_sort skater: an r package for snp-based kinship analysis, testing, and evaluation
topic Software Tool Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844523/
https://www.ncbi.nlm.nih.gov/pubmed/35222994
http://dx.doi.org/10.12688/f1000research.76004.1
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