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Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses

Intratumor heterogeneity (ITH) stands as one of the main difficulties in the treatment of colorectal cancer (CRC) as it causes the development of resistant clones and leads to heterogeneous drug responses. Here, 12 sets of patient‐derived organoids (PDOs) and cell lines (PDCs) isolated from multiple...

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Detalles Bibliográficos
Autores principales:	Kim, Soon‐Chan, Park, Ji Won, Seo, Ha‐Young, Kim, Minjung, Park, Jae‐Hyeon, Kim, Ga‐Hye, Lee, Ja Oh, Shin, Young‐Kyoung, Bae, Jeong Mo, Koo, Bon‐Kyoung, Jeong, Seung‐Yong, Ku, Ja‐Lok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844556/ https://www.ncbi.nlm.nih.gov/pubmed/34918496 http://dx.doi.org/10.1002/advs.202103360

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