Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD(+) without impacting respiratory capacity or insulin sensitivity

In clinical trials, oral supplementation with nicotinamide riboside (NR) fails to increase muscle mitochondrial respiratory capacity and insulin sensitivity but also does not increase muscle NAD(+) levels. This study tests the feasibility of chronically elevating skeletal muscle NAD(+) in mice and i...

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Detalles Bibliográficos
Autores principales: Damgaard, Mads V., Nielsen, Thomas S., Basse, Astrid L., Chubanava, Sabina, Trost, Kajetan, Moritz, Thomas, Dellinger, Ryan W., Larsen, Steen, Treebak, Jonas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844641/
https://www.ncbi.nlm.nih.gov/pubmed/35198907
http://dx.doi.org/10.1016/j.isci.2022.103863

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