Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy

Renal tubular epithelial cells (RTECs) are one of the most mitochondria-rich cell types, and are thus vulnerable to mitochondrial dysregulation, which is defined as a pivotal event in tubular damage in diabetic nephropathy (DN). However, the underlying mechanisms remain largely unknown. Here, we inv...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Bai, Fang, Song, Hui, Xiao, Rong, Wang, Yuzhen, Yang, Huimin, Ren, Xiaolei, Li, Shuangjie, Gao, Lifen, Ma, Chunhong, Yang, Xiangdong, Liang, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844679/
https://www.ncbi.nlm.nih.gov/pubmed/35152003
http://dx.doi.org/10.1016/j.redox.2022.102260

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