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Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
BACKGROUND: Calcium plays a role in a wide range of biological functions. Here we conducted a phenome-wide Mendelian randomisation (MR-PheWAS) analysis and a systematic review for MR studies to comprehensively investigate the health effects of serum calcium. METHODS: One-hundred and thirty genetic v...
Autores principales: | Yuan, Shuai, Yu, Lili, Gou, Wanglong, Wang, Lijuan, Sun, Jing, Li, Doudou, Lu, Ying, Cai, Xiaxia, Yu, Huanling, Yuan, Changzheng, Zheng, Ju-sheng, Larsson, Susanna C., Theodoratou, Evropi, Li, Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844774/ https://www.ncbi.nlm.nih.gov/pubmed/35134646 http://dx.doi.org/10.1016/j.ebiom.2022.103865 |
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