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Pten haploinsufficiency causes desynchronized growth of brain areas involved in sensory processing

How changes in brain scaling relate to altered behavior is an important question in neurodevelopmental disorder research. Mice with germline Pten haploinsufficiency (Pten(+/-)) closely mirror the abnormal brain scaling and behavioral deficits seen in humans with macrocephaly/autism syndrome, which i...

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Detalles Bibliográficos
Autores principales:	Clipperton-Allen, Amy E., Swick, Hannah, Botero, Valentina, Aceti, Massimiliano, Ellegood, Jacob, Lerch, Jason P., Page, Damon T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844819/ https://www.ncbi.nlm.nih.gov/pubmed/35198865 http://dx.doi.org/10.1016/j.isci.2022.103796

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