SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites

SARM1 is an NAD(P) glycohydrolase and TLR adapter with an essential, prodegenerative role in programmed axon death (Wallerian degeneration). Like other NAD(P)ases, it catalyzes multiple reactions that need to be fully investigated. Here, we compare these multiple activities for recombinant human SAR...

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Detalles Bibliográficos
Autores principales: Angeletti, Carlo, Amici, Adolfo, Gilley, Jonathan, Loreto, Andrea, Trapanotto, Antonio G., Antoniou, Christina, Merlini, Elisa, Coleman, Michael P., Orsomando, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844822/
https://www.ncbi.nlm.nih.gov/pubmed/35198877
http://dx.doi.org/10.1016/j.isci.2022.103812

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