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Exosomal PD-L1 induces osteogenic differentiation and promotes fracture healing by acting as an immunosuppressant

A moderate inflammatory response at the early stages of fracture healing is necessary for callus formation. Over-active and continuous inflammation, however, impairs fracture healing and leads to excessive tissue damage. Adequate fracture healing could be promoted through suppression of local over-a...

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Detalles Bibliográficos
Autores principales: Lin, Ze, Xiong, Yuan, Meng, Weilin, Hu, Yiqiang, Chen, Lili, Chen, Lang, Xue, Hang, Panayi, Adriana C., Zhou, Wu, Sun, Yun, Cao, Faqi, Liu, Guodong, Hu, Liangcong, Yan, Chenchen, Xie, Xudong, Lin, Chuanchuan, Cai, Kaiyong, Feng, Qian, Mi, Bobin, Liu, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844834/
https://www.ncbi.nlm.nih.gov/pubmed/35224310
http://dx.doi.org/10.1016/j.bioactmat.2021.10.042