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Giant symptomatic adrenal myelolipoma: A case report

INTRODUCTION: Adrenal myelolipomas are rare non-functioning benign tumors composed of adipose and hematopoietic tissues. Most AMLs are discovered incidentally and represent the second most common adrenal incidentaloma. CASE PRESENTATION: A 58-years-old female patient, obese with a history of diabete...

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Autores principales: Ramdani, Abdelbassir, Aissaoui, Asmae, Bouhout, Tariq, Bennani, Amal, Latrech, Hanane, Serji, Badr, El Harroudi, Tijani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844840/
https://www.ncbi.nlm.nih.gov/pubmed/35198182
http://dx.doi.org/10.1016/j.amsu.2022.103333
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author Ramdani, Abdelbassir
Aissaoui, Asmae
Bouhout, Tariq
Bennani, Amal
Latrech, Hanane
Serji, Badr
El Harroudi, Tijani
author_facet Ramdani, Abdelbassir
Aissaoui, Asmae
Bouhout, Tariq
Bennani, Amal
Latrech, Hanane
Serji, Badr
El Harroudi, Tijani
author_sort Ramdani, Abdelbassir
collection PubMed
description INTRODUCTION: Adrenal myelolipomas are rare non-functioning benign tumors composed of adipose and hematopoietic tissues. Most AMLs are discovered incidentally and represent the second most common adrenal incidentaloma. CASE PRESENTATION: A 58-years-old female patient, obese with a history of diabetes and blood hypertension presented with complaints of pain in the left flank. Abdominopelvic computed tomography showed a giant well-defined mass of the left adrenal gland with fat density suggesting adrenal myelolipoma. The patient underwent open left adrenalectomy. The pathological study confirmed the diagnosis of adrenal myelolipoma. DISCUSSION: Most AMLs are asymptomatic, remain stable in size, or grow slowly. Mass effect symptoms and spontaneous rupture are observed more in larger AMLs. The most common symptoms observed are abdominal discomfort/pain, hypochondrial pain, and flank pain. Most of the AMLs are discovered incidentally and the radiological features are accurate in diagnosing AML in up to 90% of the cases, CT is more sensitive for detection than other imaging modalities. The open surgery approach is the standard treatment of choice for giant AML (>10cm) while the minimally invasive approach has been used in only a few cases. CONCLUSION: The therapeutic management is discussed on a case-by-case basis. Surgical treatment is indicated for larger, symptomatic, or rapidly growing AMLs. Meanwhile smaller and asymptomatic AMLs are managed conservatively.
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spelling pubmed-88448402022-02-22 Giant symptomatic adrenal myelolipoma: A case report Ramdani, Abdelbassir Aissaoui, Asmae Bouhout, Tariq Bennani, Amal Latrech, Hanane Serji, Badr El Harroudi, Tijani Ann Med Surg (Lond) Case Report INTRODUCTION: Adrenal myelolipomas are rare non-functioning benign tumors composed of adipose and hematopoietic tissues. Most AMLs are discovered incidentally and represent the second most common adrenal incidentaloma. CASE PRESENTATION: A 58-years-old female patient, obese with a history of diabetes and blood hypertension presented with complaints of pain in the left flank. Abdominopelvic computed tomography showed a giant well-defined mass of the left adrenal gland with fat density suggesting adrenal myelolipoma. The patient underwent open left adrenalectomy. The pathological study confirmed the diagnosis of adrenal myelolipoma. DISCUSSION: Most AMLs are asymptomatic, remain stable in size, or grow slowly. Mass effect symptoms and spontaneous rupture are observed more in larger AMLs. The most common symptoms observed are abdominal discomfort/pain, hypochondrial pain, and flank pain. Most of the AMLs are discovered incidentally and the radiological features are accurate in diagnosing AML in up to 90% of the cases, CT is more sensitive for detection than other imaging modalities. The open surgery approach is the standard treatment of choice for giant AML (>10cm) while the minimally invasive approach has been used in only a few cases. CONCLUSION: The therapeutic management is discussed on a case-by-case basis. Surgical treatment is indicated for larger, symptomatic, or rapidly growing AMLs. Meanwhile smaller and asymptomatic AMLs are managed conservatively. Elsevier 2022-02-09 /pmc/articles/PMC8844840/ /pubmed/35198182 http://dx.doi.org/10.1016/j.amsu.2022.103333 Text en © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Ramdani, Abdelbassir
Aissaoui, Asmae
Bouhout, Tariq
Bennani, Amal
Latrech, Hanane
Serji, Badr
El Harroudi, Tijani
Giant symptomatic adrenal myelolipoma: A case report
title Giant symptomatic adrenal myelolipoma: A case report
title_full Giant symptomatic adrenal myelolipoma: A case report
title_fullStr Giant symptomatic adrenal myelolipoma: A case report
title_full_unstemmed Giant symptomatic adrenal myelolipoma: A case report
title_short Giant symptomatic adrenal myelolipoma: A case report
title_sort giant symptomatic adrenal myelolipoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844840/
https://www.ncbi.nlm.nih.gov/pubmed/35198182
http://dx.doi.org/10.1016/j.amsu.2022.103333
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