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Generation of human induced pluripotent stem cell-derived cerebral organoids for cellular and molecular characterization

Human induced pluripotent stem cell (hiPSC)-derived cerebral organoids (COs) can serve as an in vitro model for studying normal and pathologic human brain development. Here, we optimized existing protocols to streamline the generation of forebrain COs from hiPSCs. We employ these COs to define the i...

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Detalles Bibliográficos
Autores principales:	Anastasaki, Corina, Wilson, Anna F., Chen, Alexander S., Wegscheid, Michelle L., Gutmann, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844852/ https://www.ncbi.nlm.nih.gov/pubmed/35199037 http://dx.doi.org/10.1016/j.xpro.2022.101173

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