The Human Nose Organoid Respiratory Virus Model: an Ex Vivo Human Challenge Model To Study Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pathogenesis and Evaluate Therapeutics

There is an unmet need for preclinical models to understand the pathogenesis of human respiratory viruses and predict responsiveness to immunotherapies. Airway organoids can serve as an ex vivo human airway model to study respiratory viral pathogenesis; however, they rely on invasive techniques to o...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajan, Anubama, Weaver, Ashley Morgan, Aloisio, Gina Marie, Jelinski, Joseph, Johnson, Hannah L., Venable, Susan F., McBride, Trevor, Aideyan, Letisha, Piedra, Felipe-Andrés, Ye, Xunyan, Melicoff-Portillo, Ernestina, Yerramilli, Malli Rama Kanthi, Zeng, Xi-Lei, Mancini, Michael A., Stossi, Fabio, Maresso, Anthony W., Kotkar, Shalaka A., Estes, Mary K., Blutt, Sarah, Avadhanula, Vasanthi, Piedra, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844923/
https://www.ncbi.nlm.nih.gov/pubmed/35164569
http://dx.doi.org/10.1128/mbio.03511-21

Ejemplares similares

Ejemplares similares