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In Silico and Ex Vivo Analyses of the Inhibitory Action of the Alzheimer Drug Posiphen and Primary Metabolites with Human Acetyl- and Butyrylcholinesterase Enzymes

[Image: see text] Alzheimer’s disease (AD) is the most common neurodegenerative disorder worldwide. Ongoing research to develop AD treatments has characterized multiple drug targets including the cholinergic system, amyloid-β peptide, phosphorylated tau, and neuroinflammation. These systems have the...

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Detalles Bibliográficos
Autores principales:	Batool, Sidra, Furqan, Tiyyaba, Hasan Mahmood, Muhammad Sibte, Tweedie, David, Kamal, Mohammad A., Greig, Nigel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845043/ https://www.ncbi.nlm.nih.gov/pubmed/35178511 http://dx.doi.org/10.1021/acsptsci.1c00200

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