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Cu(I)-Catalyzed Alkynylation of Quinolones

[Image: see text] Herein we report the first alkynylation of quinolones with terminal alkynes under mild reaction conditions. The reaction is catalyzed by Cu(I) salts in the presence of a Lewis acid, which is essential for the reactivity of the system. The enantioselective version of this transforma...

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Detalles Bibliográficos
Autores principales: Maestro, Aitor, Lemaire, Sebastien, Harutyunyan, Syuzanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845045/
https://www.ncbi.nlm.nih.gov/pubmed/35099185
http://dx.doi.org/10.1021/acs.orglett.2c00020

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