MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1(G93A) Motor Neuron of Amyotrophic Lateral Sclerosis

BACKGROUND: Oxidative stress and reactive oxygen species (ROS) are important in the pathogenesis of amyotrophic lateral sclerosis (ALS). Hypochlorous acid (HOCl) is a powerful oxidant of the reactive oxygen species (ROS) family. HOCl's role in the progress of ALS remains unclear due to the lack...

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Detalles Bibliográficos
Autores principales: Peng, Jialing, Pan, Jingrui, Mo, Jingjing, Peng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845144/
https://www.ncbi.nlm.nih.gov/pubmed/35178161
http://dx.doi.org/10.1155/2022/8217663

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