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Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis

BACKGROUND: Osimertinib resistance limits the treatment of epidermal growth factor receptor-(EGFR)-mutated non-small-cell lung carcinoma (NSCLC). The mechanisms of osimertinib resistance need to be elucidated to determine alternative treatment strategies. This study explores the role of M2 type tumo...

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Detalles Bibliográficos
Autores principales:	Wan, Xiaoying, Xie, Boxiong, Sun, Hui, Gu, Weiqing, Wang, Chunyan, Deng, Qinfang, Zhou, Songwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845243/ https://www.ncbi.nlm.nih.gov/pubmed/35168607 http://dx.doi.org/10.1186/s12935-022-02509-x

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