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Rituximab in combination with gemcitabine plus cisplatin in patients with recurrent and metastatic head and neck squamous cell carcinoma: a phase I trial
BACKGROUND: The treatment of recurrent or metastatic head and neck squamous-cell carcinoma (R/M HNSCC) remains challenging. Preclinical studies revealed that B cell depletion could modulate the microenvironment and overcome chemoresistance. We conducted a phase I study to evaluate the feasibility an...
Autores principales: | Hsieh, Ching-Yun, Lien, Ming-Yu, Lin, Chen-Yuan, Lo, Wen-Jyi, Hua, Chung-Hung, Chang, Wei-Chao, Chiu, Chang-Fang, Lin, Ching-Chan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845344/ https://www.ncbi.nlm.nih.gov/pubmed/35168547 http://dx.doi.org/10.1186/s12885-022-09258-0 |
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