Cargando…

Safranal Prevents Liver Cancer Through Inhibiting Oxidative Stress and Alleviating Inflammation

Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural products and their derived biomolecules are potential resources to mine for novel anti-cancer drugs. Chemopreventive effects of safranal, a major bioactive ingredient of the golden spice “saffron”, were ev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdalla, Youssef, Abdalla, Ali, Hamza, Alaaeldin Ahmed, Amin, Amr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845597/ https://www.ncbi.nlm.nih.gov/pubmed/35177980 http://dx.doi.org/10.3389/fphar.2021.777500

Ejemplares similares

Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation
por: Lertnimitphun, Peeraphong, et al.
Publicado: (2019)

Hawthorn Herbal Preparation from Crataegus oxyacantha Attenuates In Vivo Carbon Tetrachloride -Induced Hepatic Fibrosis via Modulating Oxidative Stress and Inflammation
por: Hamza, Alaaeldin Ahmed, et al.
Publicado: (2020)

Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights
por: Abdalla, Ali, et al.
Publicado: (2022)

Effect of safranal on the response of cancer cells to topoisomerase I inhibitors: Does sequence matter?
por: Lozon, Lama, et al.
Publicado: (2022)

Ginsenoside Rb1 Alleviates Alcohol-Induced Liver Injury by Inhibiting Steatosis, Oxidative Stress, and Inflammation
por: Lai, Yuqi, et al.
Publicado: (2021)

Safranal Induces Vasorelaxation by Inhibiting Ca(2+) Influx and Na(+)/Ca(2+) Exchanger in Isolated Rat Aortic Rings
por: Al-Saigh, Noor Nadhim, et al.
Publicado: (2022)

Safranal Alleviated OVA-Induced Asthma Model and Inhibits Mast Cell Activation
por: Lertnimitphun, Peeraphong, et al.
Publicado: (2021)

Limonin Alleviates Non-alcoholic Fatty Liver Disease by Reducing Lipid Accumulation, Suppressing Inflammation and Oxidative Stress
por: Li, Yunjia, et al.
Publicado: (2022)

Trypsin inhibitor LH011 inhibited DSS-induced mice colitis via alleviating inflammation and oxidative stress
por: Jia, Zhenmao, et al.
Publicado: (2022)

Skeletal Muscle Atrophy Was Alleviated by Salidroside Through Suppressing Oxidative Stress and Inflammation During Denervation
por: Huang, Ziwei, et al.
Publicado: (2019)

Kinsenoside Alleviates Alcoholic Liver Injury by Reducing Oxidative Stress, Inhibiting Endoplasmic Reticulum Stress, and Regulating AMPK-Dependent Autophagy
por: Gao, Limin, et al.
Publicado: (2022)

BM-MSCs alleviate diabetic nephropathy in male rats by regulating ER stress, oxidative stress, inflammation, and apoptotic pathways
por: Khamis, Tarek, et al.
Publicado: (2023)

Dexamethasone Pretreatment Alleviates Isoniazid/Lipopolysaccharide Hepatotoxicity: Inhibition of Inflammatory and Oxidative Stress
por: Hassan, Hozeifa M., et al.
Publicado: (2017)

Preventive effect of safranal against oxidative damage in aged male rat brain
por: Samarghandian, Saeed, et al.
Publicado: (2014)

The legacy of Jeremy Safran
por: Lingiardi, Vittorio, et al.
Publicado: (2019)

BNTA alleviates inflammatory osteolysis by the SOD mediated anti-oxidation and anti-inflammation effect on inhibiting osteoclastogenesis
por: Wang, Huidong, et al.
Publicado: (2022)

Ginsenoside Rc, as an FXR activator, alleviates acetaminophen-induced hepatotoxicity via relieving inflammation and oxidative stress
por: Zhong, Yadi, et al.
Publicado: (2022)

Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR
por: Huangfu, Yaru, et al.
Publicado: (2023)

Bioactive Guided Fractions of Annona reticulata L. bark: Protection against Liver Toxicity and Inflammation through Inhibiting Oxidative Stress and Proinflammatory Cytokines
por: Kandimalla, Raghuram, et al.
Publicado: (2016)

Hepatoprotective Potential of Pomegranate in Curbing the Incidence of Acute Liver Injury by Alleviating Oxidative Stress and Inflammatory Response
por: Ali, Hamid, et al.
Publicado: (2021)

The Pathogenesis of Diabetes Mellitus by Oxidative Stress and Inflammation: Its Inhibition by Berberine
por: Ma, Xueling, et al.
Publicado: (2018)

Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/ PPARα-NF-κB/IR-S2 signaling pathway
por: Reda, Doha, et al.
Publicado: (2023)

Alleviating effects of coenzyme Q10 supplements on biomarkers of inflammation and oxidative stress: results from an umbrella meta-analysis
por: Dabbaghi Varnousfaderani, Sara, et al.
Publicado: (2023)

Silibinin alleviates intestinal inflammation via inhibiting JNK signaling in Drosophila
por: Yan, La, et al.
Publicado: (2023)

Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat–High fructose diet
por: García-Berumen, Claudia Isabel, et al.
Publicado: (2022)

Protective Effects of Casticin From Vitex trifolia Alleviate Eosinophilic Airway Inflammation and Oxidative Stress in a Murine Asthma Model
por: Liou, Chian-Jiun, et al.
Publicado: (2018)

Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects
por: Liu, Zhaoguo, et al.
Publicado: (2022)

Phytochemical and anti-neuropathic investigations of Crocus sativus via alleviating inflammation, oxidative stress and pancreatic beta-cells regeneration
por: Raafat, Karim, et al.
Publicado: (2019)

Characterization of human serum albumin's interactions with safranal and crocin using multi-spectroscopic and molecular docking techniques
por: Salem, Alaa A., et al.
Publicado: (2019)

The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review
por: Nanda, Sanju, et al.
Publicado: (2021)

Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation
por: Yao, Hong, et al.
Publicado: (2017)

Evaluation of Lung and Bronchoalveolar Lavage Fluid Oxidative Stress Indices for Assessing the Preventing Effects of Safranal on Respiratory Distress in Diabetic Rats
por: Samarghandian, Saeed, et al.
Publicado: (2014)

Puerarin inhibited oxidative stress and alleviated cerebral ischemia-reperfusion injury through PI3K/Akt/Nrf2 signaling pathway
por: Zhang, Qianqian, et al.
Publicado: (2023)

Piper sarmentosum Roxb. methanolic extract prevents stress-induced gastric ulcer by modulating oxidative stress and inflammation
por: Akmal, Muhamad Nurul, et al.
Publicado: (2023)

Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inﬂammation, and Oxidative Stress
por: Wang, Hao, et al.
Publicado: (2020)

Inhibition of 5-Lipoxygenase in Hepatic Stellate Cells Alleviates Liver Fibrosis
por: Pu, Shiyun, et al.
Publicado: (2021)

Specific Inhibition of CYP4A Alleviates Myocardial Oxidative Stress and Apoptosis Induced by Advanced Glycation End-Products
por: Wang, Rui, et al.
Publicado: (2019)

Affinity-based target deconvolution of safranal
por: Hosseinzadeh, Hossein, et al.
Publicado: (2013)

Jeremy Safran: a hero’s journey
por: Horvath, Adam Otto
Publicado: (2019)

Pharmacological effects of Safranal: An updated review
por: Esmaealzadeh, Danial, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v1etlasmdp20nm6j86g1v6u874