Cargando…

Integrated Metabolomics and Network Pharmacology Revealed Hong-Hua-Xiao-Yao Tablet’s Effect of Mediating Hormone Synthesis in the Treatment of Mammary Gland Hyperplasia

Hong-Hua-Xiao-Yao Tablet (HHXYT) is a traditional Chinese medicine (TCM) formula that has been approved for the treatment of mammary gland hyperplasia (MGH), but its mechanism of action is unclear. In this study, a strategy that integrated metabolomics and network pharmacology was applied to systemi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Ziqing, Mi, Rui, Cheng, Zhaoxi, Li, Xiaofeng, Zeng, Huawu, Wu, Gaosong, Zhao, Jing, Zhang, Weidong, Ye, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846323/ https://www.ncbi.nlm.nih.gov/pubmed/35177987 http://dx.doi.org/10.3389/fphar.2022.788019

Ejemplares similares

Integrating Metabolomics and Network Pharmacology to Explore the Mechanism of Xiao-Yao-San in the Treatment of Inflammatory Response in CUMS Mice
por: Zhang, Yi, et al.
Publicado: (2023)

An Integrated Pharmacology-Based Analysis for Antidepressant Mechanism of Chinese Herbal Formula Xiao-Yao-San
por: Yuan, Naijun, et al.
Publicado: (2020)

Effects of Jia-Wei-Xiao-Yao-San on the Peripheral and Lymphatic Pharmacokinetics of Paclitaxel in Rats
por: Hou, Mei-Ling, et al.
Publicado: (2016)

Xiao-Yao-San Formula Improves Cognitive Ability by Protecting the Hippocampal Neurons in Ovariectomized Rats
por: Liu, Lina, et al.
Publicado: (2020)

Clinical efficacy and safety of traditional Chinese medicine Xiao Yao San in insomnia combined with anxiety
por: Hu, Jing, et al.
Publicado: (2021)

Chinese Herbal Formula Xiao Yao San for Treatment of Depression: A Systematic Review of Randomized Controlled Trials
por: Zhang, Yuqing, et al.
Publicado: (2012)

Evaluation of the Safety and Efficacy of Xiao Yao San as a Treatment for Anxiety: A Systematic Review and Meta-Analysis
por: Lin, Jin, et al.
Publicado: (2022)

Efficacy and safety of the Chinese herbal medicine Xiao Yao San for treating anxiety: a systematic review with meta-analysis and trial sequential analysis
por: Wang, Yifan, et al.
Publicado: (2023)

A Chinese Herbal Medicine, Jia-Wei-Xiao-Yao-San, Prevents Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats
por: Chien, Shu-Chen, et al.
Publicado: (2014)

Identification of absorbed compounds of Xiao Yao San Jia Wei and pharmacokinetic study in depressed rats by force swimming stress
por: Shan, Chenxiao, et al.
Publicado: (2022)

Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of β-Arrestin 2-Mediated Pathways in Hippocampus
por: Zhu, Xiaoxia, et al.
Publicado: (2014)

Xiao Yao San against Corticosterone-Induced Stress Injury via Upregulating Glucocorticoid Receptor Reaction Element Transcriptional Activity
por: Cao, Guoping, et al.
Publicado: (2016)

Xiao-Yao-San, a Chinese Medicine Formula, Ameliorates Chronic Unpredictable Mild Stress Induced Polycystic Ovary in Rat
por: Sun, Hao-Yu, et al.
Publicado: (2017)

Effect of Hua Yu Xiao Zheng decoction on the expression levels of vascular endothelial growth factor and angiopoietin-2 in rats with endometriosis
por: Chen, Zhen-Zhen, et al.
Publicado: (2017)

XiaoEr LianHuaQinqGan alleviates viral pneumonia in mice infected by influenza A and respiratory syncytial viruses
por: Li, Wenyan, et al.
Publicado: (2022)

Room-temperature super-extraction system (RTSES) optimizes the anxiolytic- and antidepressant-like behavioural effects of traditional Xiao-Yao-San in mice
por: Yin, Shih-Hsi, et al.
Publicado: (2012)

Xiao Yao San Improves Depressive-Like Behaviors in Rats with Chronic Immobilization Stress through Modulation of Locus Coeruleus-Norepinephrine System
por: Ding, Xiu-Fang, et al.
Publicado: (2014)

Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of Xiao Yao san on chronically stressed mice
por: Ding, Xiu-Fang, et al.
Publicado: (2017)

Xiao-Yao-San protects against anti-tuberculosis drug-induced liver injury by regulating Grsf1 in the mitochondrial oxidative stress pathway
por: Bai, Zijun, et al.
Publicado: (2022)

Retraction Note: Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of Xiao Yao san on chronically stressed mice
por: Ding, Xiu-Fang, et al.
Publicado: (2023)

Herb-Drug Pharmacokinetic Interaction of a Traditional Chinese Medicine Jia-Wei-Xiao-Yao-San with 5-Fluorouracil in the Blood and Brain of Rat Using Microdialysis
por: Chiang, Meng-Hsuan, et al.
Publicado: (2015)

Efficacy and Safety of Chinese Herbal Medicine Xiao Yao San in Functional Gastrointestinal Disorders: A meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials
por: Liu, Qian, et al.
Publicado: (2022)

Clinical observation of Dan-Hong Hua-Yu oral solution in treating retinal vein occlusion
por: Li, Tie-Jun, et al.
Publicado: (2020)

The in vivo Therapeutic Effect of Free Wanderer Powder (逍遙散 xiāo yáo sǎn, Xiaoyaosan) on Mice with 4T1 Cell Induced Breast Cancer Model
por: Chen, Wen-Fang, et al.
Publicado: (2012)

Corrigenda: Jiao TY, Yao QY, Xiao H (2017) Review of Dibrachys Förster from China (Hymenoptera, Chalcidoidea, Pteromalidae). ZooKeys 656: 123–149.
por: Jiao, Tian-yang, et al.
Publicado: (2017)

The Infrared Radiation Temperature Characteristic of Acupoints of Mammary Gland Hyperplasia Patients
por: Zheng, Juanjuan, et al.
Publicado: (2013)

Molecular Targets and Associated Potential Pathways of Danlu Capsules in Hyperplasia of Mammary Glands Based on Systems Pharmacology
por: Huang, Jihan, et al.
Publicado: (2017)

Evaluation of the mechanism of Rujiling capsules in the treatment of hyperplasia of mammary glands based on network pharmacology and molecular docking
por: Shi, Mili, et al.
Publicado: (2022)

Xin hua jing /
Publicado: (1982)

Acupuncture for mammary gland hyperplasia: A Bayesian network meta-analysis protocol
por: Xiong, Jun, et al.
Publicado: (2020)

Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia
por: Pang, Han-Qing, et al.
Publicado: (2018)

Mechanisms of single herbs and herbal pairs in the treatment of mammary gland hyperplasia: An integrated review()
por: Yang, Xujie, et al.
Publicado: (2023)

Effect of Saffron (Fan Hong Hua) On the Readiness of The Uterine Cervix In Term Pregnancy: A Placebo-Controlled Randomized Trial
por: Sadi, Roghaieh, et al.
Publicado: (2016)

Treatment of refractory Yao syndrome with canakinumab
por: Brailsford, Caroline J., et al.
Publicado: (2022)

Metabolomic profiles in yak mammary gland tissue during the lactation cycle
por: Li, Zhixiong, et al.
Publicado: (2019)

Physicochemical, Nutritional Properties and Metabolomics Analysis Fat Deposition Mechanism of Chahua Chicken No. 2 and Yao Chicken
por: Liu, Yong, et al.
Publicado: (2022)

A Study of Using Massage Therapy Accompanied with Stretching Exercise for Rehabilitation of Mammary Gland Hyperplasia
por: Lv, Pin, et al.
Publicado: (2016)

The Modulatory Properties of Li-Ru-Kang Treatment on Hyperplasia of Mammary Glands Using an Integrated Approach
por: Wei, Shizhang, et al.
Publicado: (2018)

MicroRNA array analysis of the regulation of microRNAs in rats exhibiting hyperplasia of mammary glands
por: Gu, Liyan, et al.
Publicado: (2018)

Massage treatment of hyperplasia of mammary glands: A protocol for a systematic review and meta-analysis
por: Ma, Dehui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_iokie1fsfqak19p7l6scift0kg