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Structural Optimization and Improving Antitumor Potential of Moreollic Acid from Gamboge
Moreollic acid, a caged-tetraprenylated xanthone from Gamboge, has been indicated as a potent antitumor molecule. In the present study, a series of moreollic acid derivatives with novel structures were designed and synthesized, and their antitumor activities were determined in multifarious cell line...
Autores principales: | Cheng, Li-Zhi, Huang, Dan-Ling, Liao, Min, Li, Ke-Ming, Wu, Zhao-Qiu, Cheng, Yong-Xian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846360/ https://www.ncbi.nlm.nih.gov/pubmed/35056797 http://dx.doi.org/10.3390/molecules27020482 |
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