In Vitro Activity of Gepotidacin against Gram-Negative and Gram-Positive Anaerobes

Gepotidacin (formerly GSK2140944) is a first-in-class triazaacenaphthylene antibacterial currently in phase III clinical trials. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, gepotidacin inhibited 90% of isolates at concentrations of 4 and 2 μg/m...

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Detalles Bibliográficos
Autores principales: Hackel, Meredith A., Karlowsky, James A., Canino, Michele A., Sahm, Daniel F., Scangarella-Oman, Nicole E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Susceptibility
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846401/
https://www.ncbi.nlm.nih.gov/pubmed/34930028
http://dx.doi.org/10.1128/aac.02165-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846401/
https://www.ncbi.nlm.nih.gov/pubmed/34930028
http://dx.doi.org/10.1128/aac.02165-21

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