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In Vitro Activity of Gepotidacin against Gram-Negative and Gram-Positive Anaerobes
Gepotidacin (formerly GSK2140944) is a first-in-class triazaacenaphthylene antibacterial currently in phase III clinical trials. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, gepotidacin inhibited 90% of isolates at concentrations of 4 and 2 μg/m...
Autores principales: | Hackel, Meredith A., Karlowsky, James A., Canino, Michele A., Sahm, Daniel F., Scangarella-Oman, Nicole E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846401/ https://www.ncbi.nlm.nih.gov/pubmed/34930028 http://dx.doi.org/10.1128/aac.02165-21 |
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