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SALVAGE SURGERY IN GASTRIC CANCER

Salvage surgery (SS) is defined as surgical resection after the failure of the first treatment with curative intent. AIM: The aim of this study was to report the experience of a reference center with SS for stomach adenocarcinoma. METHODS: This is a retrospective study of patients with gastric cance...

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Autores principales: SIMÕES, Italo Beltrão Pereira, PEREIRA, Marina Alessandra, RAMOS, Marcus Fernando Kodama Pertille, RIBEIRO, Ulysses, ZILBERSTEIN, Bruno, NAHAS, Sergio Carlos, DIAS, Andre Roncon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846409/
https://www.ncbi.nlm.nih.gov/pubmed/35107491
http://dx.doi.org/10.1590/0102-672020210002e1629
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author SIMÕES, Italo Beltrão Pereira
PEREIRA, Marina Alessandra
RAMOS, Marcus Fernando Kodama Pertille
RIBEIRO, Ulysses
ZILBERSTEIN, Bruno
NAHAS, Sergio Carlos
DIAS, Andre Roncon
author_facet SIMÕES, Italo Beltrão Pereira
PEREIRA, Marina Alessandra
RAMOS, Marcus Fernando Kodama Pertille
RIBEIRO, Ulysses
ZILBERSTEIN, Bruno
NAHAS, Sergio Carlos
DIAS, Andre Roncon
author_sort SIMÕES, Italo Beltrão Pereira
collection PubMed
description Salvage surgery (SS) is defined as surgical resection after the failure of the first treatment with curative intent. AIM: The aim of this study was to report the experience of a reference center with SS for stomach adenocarcinoma. METHODS: This is a retrospective study of patients with gastric cancer (GC) operated on between 2009 and 2020. RESULTS: Notably, 40 patients were recommended for salvage gastrectomy with curative-intent treatment. For analysis purpose, patients were divided into two groups: 23 patients after endoscopic resection and 17 patients after gastrectomy. In the first group, all patients underwent R0 resection, their average hospital length of stay (LOS) was 15.7 days, and 2 (8.6%) patients had major complications. During the average follow-up of 37.2 months, there was only one recurrence. The median overall survival (OS) was 46 months. In the postgastrectomy group, 9 (52.9%) patients were rescued with curative intent, the average hospital LOS was 12.2 days, and 3 (17.6%) had major complications. In a mean follow-up of 22 months, five patients relapsed. Median OS and disease-free survival were 24 and 16.5 months, respectively. CONCLUSION: SS in GC offers the possibility of long-term disease control and increased survival rate with an acceptable complication rate.
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spelling pubmed-88464092022-02-28 SALVAGE SURGERY IN GASTRIC CANCER SIMÕES, Italo Beltrão Pereira PEREIRA, Marina Alessandra RAMOS, Marcus Fernando Kodama Pertille RIBEIRO, Ulysses ZILBERSTEIN, Bruno NAHAS, Sergio Carlos DIAS, Andre Roncon Arq Bras Cir Dig Artigo Original Salvage surgery (SS) is defined as surgical resection after the failure of the first treatment with curative intent. AIM: The aim of this study was to report the experience of a reference center with SS for stomach adenocarcinoma. METHODS: This is a retrospective study of patients with gastric cancer (GC) operated on between 2009 and 2020. RESULTS: Notably, 40 patients were recommended for salvage gastrectomy with curative-intent treatment. For analysis purpose, patients were divided into two groups: 23 patients after endoscopic resection and 17 patients after gastrectomy. In the first group, all patients underwent R0 resection, their average hospital length of stay (LOS) was 15.7 days, and 2 (8.6%) patients had major complications. During the average follow-up of 37.2 months, there was only one recurrence. The median overall survival (OS) was 46 months. In the postgastrectomy group, 9 (52.9%) patients were rescued with curative intent, the average hospital LOS was 12.2 days, and 3 (17.6%) had major complications. In a mean follow-up of 22 months, five patients relapsed. Median OS and disease-free survival were 24 and 16.5 months, respectively. CONCLUSION: SS in GC offers the possibility of long-term disease control and increased survival rate with an acceptable complication rate. Colégio Brasileiro de Cirurgia Digestiva 2022-01-31 /pmc/articles/PMC8846409/ /pubmed/35107491 http://dx.doi.org/10.1590/0102-672020210002e1629 Text en https://creativecommons.org/licenses/by/4.0/Este é um artigo publicado em acesso aberto sob uma licença Creative Commons
spellingShingle Artigo Original
SIMÕES, Italo Beltrão Pereira
PEREIRA, Marina Alessandra
RAMOS, Marcus Fernando Kodama Pertille
RIBEIRO, Ulysses
ZILBERSTEIN, Bruno
NAHAS, Sergio Carlos
DIAS, Andre Roncon
SALVAGE SURGERY IN GASTRIC CANCER
title SALVAGE SURGERY IN GASTRIC CANCER
title_full SALVAGE SURGERY IN GASTRIC CANCER
title_fullStr SALVAGE SURGERY IN GASTRIC CANCER
title_full_unstemmed SALVAGE SURGERY IN GASTRIC CANCER
title_short SALVAGE SURGERY IN GASTRIC CANCER
title_sort salvage surgery in gastric cancer
topic Artigo Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846409/
https://www.ncbi.nlm.nih.gov/pubmed/35107491
http://dx.doi.org/10.1590/0102-672020210002e1629
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