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A systematic review and meta-analyses of interleukin-1 receptor associated kinase 3 (IRAK3) action on inflammation in in vivo models for the study of sepsis

BACKGROUND: Interleukin-1 receptor associated kinase 3 (IRAK3) is a critical modulator of inflammation and is associated with endotoxin tolerance and sepsis. Although IRAK3 is known as a negative regulator of inflammation, several studies have reported opposing functions, and the temporal actions of...

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Detalles Bibliográficos
Autores principales: Nguyen, Trang H., Turek, Ilona, Meehan-Andrews, Terri, Zacharias, Anita, Irving, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846508/
https://www.ncbi.nlm.nih.gov/pubmed/35167625
http://dx.doi.org/10.1371/journal.pone.0263968