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A DCL3 dicing code within Pol IV-RDR2 transcripts diversifies the siRNA pool guiding RNA-directed DNA methylation

In plants, selfish genetic elements, including retrotransposons and DNA viruses, are transcriptionally silenced by RNA-directed DNA methylation. Guiding the process are short interfering RNAs (siRNAs) cut by DICER-LIKE 3 (DCL3) from double-stranded precursors of ~30 bp that are synthesized by NUCLEA...

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Detalles Bibliográficos
Autores principales: Loffer, Andrew, Singh, Jasleen, Fukudome, Akihito, Mishra, Vibhor, Wang, Feng, Pikaard, Craig S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846587/
https://www.ncbi.nlm.nih.gov/pubmed/35098919
http://dx.doi.org/10.7554/eLife.73260