Cargando…
A DCL3 dicing code within Pol IV-RDR2 transcripts diversifies the siRNA pool guiding RNA-directed DNA methylation
In plants, selfish genetic elements, including retrotransposons and DNA viruses, are transcriptionally silenced by RNA-directed DNA methylation. Guiding the process are short interfering RNAs (siRNAs) cut by DICER-LIKE 3 (DCL3) from double-stranded precursors of ~30 bp that are synthesized by NUCLEA...
Autores principales: | Loffer, Andrew, Singh, Jasleen, Fukudome, Akihito, Mishra, Vibhor, Wang, Feng, Pikaard, Craig S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846587/ https://www.ncbi.nlm.nih.gov/pubmed/35098919 http://dx.doi.org/10.7554/eLife.73260 |
Ejemplares similares
-
Identification of Pol IV and RDR2-dependent precursors of 24 nt siRNAs guiding de novo DNA methylation in Arabidopsis
por: Blevins, Todd, et al.
Publicado: (2015) -
The Pol IV largest subunit CTD quantitatively affects siRNA levels guiding RNA-directed DNA methylation
por: Wendte, Jered M, et al.
Publicado: (2019) -
A tudor domain protein, SIMR-1, promotes siRNA production at piRNA-targeted mRNAs in C. elegans
por: Manage, Kevin I, et al.
Publicado: (2020) -
Correction: Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo
por: Petrenko, Natalia, et al.
Publicado: (2017) -
p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways
por: Roy, Sunetra, et al.
Publicado: (2018)