Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice

The outcome of an encounter with Mycobacterium tuberculosis (Mtb) depends on the pathogen’s ability to adapt to the variable immune pressures exerted by the host. Understanding this interplay has proven difficult, largely because experimentally tractable animal models do not recapitulate the heterog...

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Detalles Bibliográficos
Autores principales: Smith, Clare M, Baker, Richard E, Proulx, Megan K, Mishra, Bibhuti B, Long, Jarukit E, Park, Sae Woong, Lee, Ha-Na, Kiritsy, Michael C, Bellerose, Michelle M, Olive, Andrew J, Murphy, Kenan C, Papavinasasundaram, Kadamba, Boehm, Frederick J, Reames, Charlotte J, Meade, Rachel K, Hampton, Brea K, Linnertz, Colton L, Shaw, Ginger D, Hock, Pablo, Bell, Timothy A, Ehrt, Sabine, Schnappinger, Dirk, Pardo-Manuel de Villena, Fernando, Ferris, Martin T, Ioerger, Thomas R, Sassetti, Christopher M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846590/
https://www.ncbi.nlm.nih.gov/pubmed/35112666
http://dx.doi.org/10.7554/eLife.74419

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