Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample

X-chromosomal STRs are a powerful tool to assess a broad variety of complex kinship scenarios. We introduce herewith the first Swiss X-STR dataset based on 1198 individuals (592 female, 606 male), characterized with the Qiagen Investigator® Argus X-12 QS multiplex kit. Anomalous allele patterns, all...

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Detalles Bibliográficos
Autores principales: Bottinelli, Michel, Gouy, Alexandre, Utz, Silvia, Zieger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Population Data
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847170/
https://www.ncbi.nlm.nih.gov/pubmed/34420081
http://dx.doi.org/10.1007/s00414-021-02684-y
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author Bottinelli, Michel
Gouy, Alexandre
Utz, Silvia
Zieger, Martin
author_facet Bottinelli, Michel
Gouy, Alexandre
Utz, Silvia
Zieger, Martin
author_sort Bottinelli, Michel
collection PubMed
description X-chromosomal STRs are a powerful tool to assess a broad variety of complex kinship scenarios. We introduce herewith the first Swiss X-STR dataset based on 1198 individuals (592 female, 606 male), characterized with the Qiagen Investigator® Argus X-12 QS multiplex kit. Anomalous allele patterns, allele and haplotype frequencies, and forensic and population genetic parameters are presented. We detected linkage disequilibrium within three out of the four designated linkage groups and no apparent intra-national population substructure. We compared the dataset to a global panel of X-STR datasets and it fits well in the European context, as expected. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00414-021-02684-y.
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spelling pubmed-88471702022-02-23 Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample Bottinelli, Michel Gouy, Alexandre Utz, Silvia Zieger, Martin Int J Legal Med Population Data X-chromosomal STRs are a powerful tool to assess a broad variety of complex kinship scenarios. We introduce herewith the first Swiss X-STR dataset based on 1198 individuals (592 female, 606 male), characterized with the Qiagen Investigator® Argus X-12 QS multiplex kit. Anomalous allele patterns, allele and haplotype frequencies, and forensic and population genetic parameters are presented. We detected linkage disequilibrium within three out of the four designated linkage groups and no apparent intra-national population substructure. We compared the dataset to a global panel of X-STR datasets and it fits well in the European context, as expected. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00414-021-02684-y. Springer Berlin Heidelberg 2021-08-22 2022 /pmc/articles/PMC8847170/ /pubmed/34420081 http://dx.doi.org/10.1007/s00414-021-02684-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Population Data
Bottinelli, Michel
Gouy, Alexandre
Utz, Silvia
Zieger, Martin
Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample
title Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample
title_full Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample
title_fullStr Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample
title_full_unstemmed Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample
title_short Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample
title_sort population genetic analysis of 12 x-chromosomal strs in a swiss sample
topic Population Data
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847170/
https://www.ncbi.nlm.nih.gov/pubmed/34420081
http://dx.doi.org/10.1007/s00414-021-02684-y
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