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Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men
The aims of the current study, therefore, were to compare (1) free-living MPS and (2) muscle and metabolic adaptations to resistance exercise in South Asian and white European adults. Eighteen South Asian and 16 White European men were enrolled in the study. Free-living muscle protein synthesis was...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847359/ https://www.ncbi.nlm.nih.gov/pubmed/35169204 http://dx.doi.org/10.1038/s41598-022-06446-7 |
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author | Alkhayl, Faris F. Aba Ismail, Ahmad D. Celis-Morales, Carlos Wilson, John Radjenovic, Aleksandra Johnston, Lynsey Welsh, Paul Sattar, Naveed Gill, Jason M. R. Preston, Tom Gray, Stuart R. |
author_facet | Alkhayl, Faris F. Aba Ismail, Ahmad D. Celis-Morales, Carlos Wilson, John Radjenovic, Aleksandra Johnston, Lynsey Welsh, Paul Sattar, Naveed Gill, Jason M. R. Preston, Tom Gray, Stuart R. |
author_sort | Alkhayl, Faris F. Aba |
collection | PubMed |
description | The aims of the current study, therefore, were to compare (1) free-living MPS and (2) muscle and metabolic adaptations to resistance exercise in South Asian and white European adults. Eighteen South Asian and 16 White European men were enrolled in the study. Free-living muscle protein synthesis was measured at baseline. Muscle strength, body composition, resting metabolic rate, VO(2max) and metabolic responses (insulin sensitivity) to a mixed meal were measured at baseline and following 12 weeks of resistance exercise training. Free-living muscle protein synthesis was not different between South Asians (1.48 ± 0.09%/day) and White Europeans (1.59 ± 0.15%/day) (p = 0.522). In response to resistance exercise training there were no differences, between South Asians and White Europeans, muscle mass, lower body strength or insulin sensitivity. However, there were differences between the ethnicities in response to resistance exercise training in body fat, resting carbohydrate and fat metabolism, blood pressure, VO(2max) and upper body strength with responses less favourable in South Asians. In this exploratory study there were no differences in muscle protein synthesis or anabolic and metabolic responses to resistance exercise, yet there were less favourable responses in several outcomes. These findings require further investigation. |
format | Online Article Text |
id | pubmed-8847359 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-88473592022-02-16 Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men Alkhayl, Faris F. Aba Ismail, Ahmad D. Celis-Morales, Carlos Wilson, John Radjenovic, Aleksandra Johnston, Lynsey Welsh, Paul Sattar, Naveed Gill, Jason M. R. Preston, Tom Gray, Stuart R. Sci Rep Article The aims of the current study, therefore, were to compare (1) free-living MPS and (2) muscle and metabolic adaptations to resistance exercise in South Asian and white European adults. Eighteen South Asian and 16 White European men were enrolled in the study. Free-living muscle protein synthesis was measured at baseline. Muscle strength, body composition, resting metabolic rate, VO(2max) and metabolic responses (insulin sensitivity) to a mixed meal were measured at baseline and following 12 weeks of resistance exercise training. Free-living muscle protein synthesis was not different between South Asians (1.48 ± 0.09%/day) and White Europeans (1.59 ± 0.15%/day) (p = 0.522). In response to resistance exercise training there were no differences, between South Asians and White Europeans, muscle mass, lower body strength or insulin sensitivity. However, there were differences between the ethnicities in response to resistance exercise training in body fat, resting carbohydrate and fat metabolism, blood pressure, VO(2max) and upper body strength with responses less favourable in South Asians. In this exploratory study there were no differences in muscle protein synthesis or anabolic and metabolic responses to resistance exercise, yet there were less favourable responses in several outcomes. These findings require further investigation. Nature Publishing Group UK 2022-02-15 /pmc/articles/PMC8847359/ /pubmed/35169204 http://dx.doi.org/10.1038/s41598-022-06446-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Alkhayl, Faris F. Aba Ismail, Ahmad D. Celis-Morales, Carlos Wilson, John Radjenovic, Aleksandra Johnston, Lynsey Welsh, Paul Sattar, Naveed Gill, Jason M. R. Preston, Tom Gray, Stuart R. Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men |
title | Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men |
title_full | Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men |
title_fullStr | Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men |
title_full_unstemmed | Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men |
title_short | Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men |
title_sort | muscle protein synthesis and muscle/metabolic responses to resistance exercise training in south asian and white european men |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847359/ https://www.ncbi.nlm.nih.gov/pubmed/35169204 http://dx.doi.org/10.1038/s41598-022-06446-7 |
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