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Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) continue to wreak havoc across the globe. Higher transmissibility and immunologic resistance of VOCs bring unprecedented challenges to epidemic extinguishment. Here we describe a monoclonal antibody, 2G1, that ne...

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Detalles Bibliográficos
Autores principales: Ma, Hang, Guo, Yingying, Tang, Haoneng, Tseng, Chien-Te K., Wang, Lei, Zong, Huifang, Wang, Zhenyu, He, Yang, Chang, Yunsong, Wang, Shusheng, Huang, Haiqiu, Ke, Yong, Yuan, Yunsheng, Wu, Mingyuan, Zhang, Yuanyuan, Drelich, Aleksandra, Kempaiah, Kempaiah Rayavara, Peng, Bi-Hung, Wang, Ailin, Yang, Kaiyong, Yin, Haiyang, Liu, Junjun, Yue, Yali, Xu, Wenbo, Zhu, Shuangli, Ji, Tianjiao, Zhang, Xiaoju, Wang, Ziqi, Li, Gang, Liu, Guangchun, Song, Jingjing, Mu, Lingling, Xiang, ZongShang, Song, Zhangyi, Chen, Hua, Bian, Yanlin, Zhang, Baohong, Chen, Hui, Zhang, Jiawei, Liao, Yunji, Zhang, Li, Yang, Li, Chen, Yi, Gilly, John, Xiao, Xiaodong, Han, Lei, Jiang, Hua, Xie, Yueqing, Zhou, Qiang, Zhu, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847360/
https://www.ncbi.nlm.nih.gov/pubmed/35169121
http://dx.doi.org/10.1038/s41421-022-00381-7