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A chemically-defined plastic scaffold for the xeno-free production of human pluripotent stem cells

Clinical use of human pluripotent stem cells (hPSCs) is hampered by the technical limitations of their expansion. Here, we developed a chemically synthetic culture substrate for human pluripotent stem cell attachment and maintenance. The substrate comprises a hydrophobic polyvinyl butyral-based poly...

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Detalles Bibliográficos
Autores principales: Shimizu, Eiko, Iguchi, Hiroki, Le, Minh Nguyen Tuyet, Nakamura, Yuta, Kobayashi, Daigo, Arai, Yuhei, Takakura, Kenta, Benno, Seiko, Yoshida, Noriko, Tsukahara, Masayoshi, Haneda, Satoshi, Hasegawa, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847402/
https://www.ncbi.nlm.nih.gov/pubmed/35169157
http://dx.doi.org/10.1038/s41598-022-06356-8