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COVID‐19 and venous thromboembolism: A narrative review
COVID‐19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) is associated with coagulopathy through numerous mechanisms. The reported incidence of venous thromboembolism (VTE) in hospitalized patients with COVID‐19 has varied widely, and several meta‐analyses have been performed to asses...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847419/ https://www.ncbi.nlm.nih.gov/pubmed/35224417 http://dx.doi.org/10.1002/rth2.12666 |
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author | Angelini, Dana E. Kaatz, Scott Rosovsky, Rachel P. Zon, Rebecca L. Pillai, Shreejith Robertson, William E. Elavalakanar, Pavania Patell, Rushad Khorana, Alok |
author_facet | Angelini, Dana E. Kaatz, Scott Rosovsky, Rachel P. Zon, Rebecca L. Pillai, Shreejith Robertson, William E. Elavalakanar, Pavania Patell, Rushad Khorana, Alok |
author_sort | Angelini, Dana E. |
collection | PubMed |
description | COVID‐19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) is associated with coagulopathy through numerous mechanisms. The reported incidence of venous thromboembolism (VTE) in hospitalized patients with COVID‐19 has varied widely, and several meta‐analyses have been performed to assess the overall prevalence of VTE. The novelty of this coronavirus strain along with its unique mechanisms for microvascular and macrovascular thrombosis has led to uncertainty as to how to diagnose, prevent, and treat thrombosis in patients affected by this virus. This review discusses the epidemiology and pathophysiology of thrombosis in the setting of SARS‐CoV‐2 infection along with an updated review on the preventative and treatment strategies for VTE associated with SARS‐CoV‐2 infection. |
format | Online Article Text |
id | pubmed-8847419 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88474192022-02-25 COVID‐19 and venous thromboembolism: A narrative review Angelini, Dana E. Kaatz, Scott Rosovsky, Rachel P. Zon, Rebecca L. Pillai, Shreejith Robertson, William E. Elavalakanar, Pavania Patell, Rushad Khorana, Alok Res Pract Thromb Haemost Review Article COVID‐19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) is associated with coagulopathy through numerous mechanisms. The reported incidence of venous thromboembolism (VTE) in hospitalized patients with COVID‐19 has varied widely, and several meta‐analyses have been performed to assess the overall prevalence of VTE. The novelty of this coronavirus strain along with its unique mechanisms for microvascular and macrovascular thrombosis has led to uncertainty as to how to diagnose, prevent, and treat thrombosis in patients affected by this virus. This review discusses the epidemiology and pathophysiology of thrombosis in the setting of SARS‐CoV‐2 infection along with an updated review on the preventative and treatment strategies for VTE associated with SARS‐CoV‐2 infection. John Wiley and Sons Inc. 2022-02-15 /pmc/articles/PMC8847419/ /pubmed/35224417 http://dx.doi.org/10.1002/rth2.12666 Text en © 2022 The Authors. Research and Practice in Thrombosis and Haemostasis published by Wiley Periodicals LLC on behalf of International Society on Thrombosis and Haemostasis (ISTH). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Review Article Angelini, Dana E. Kaatz, Scott Rosovsky, Rachel P. Zon, Rebecca L. Pillai, Shreejith Robertson, William E. Elavalakanar, Pavania Patell, Rushad Khorana, Alok COVID‐19 and venous thromboembolism: A narrative review |
title | COVID‐19 and venous thromboembolism: A narrative review |
title_full | COVID‐19 and venous thromboembolism: A narrative review |
title_fullStr | COVID‐19 and venous thromboembolism: A narrative review |
title_full_unstemmed | COVID‐19 and venous thromboembolism: A narrative review |
title_short | COVID‐19 and venous thromboembolism: A narrative review |
title_sort | covid‐19 and venous thromboembolism: a narrative review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847419/ https://www.ncbi.nlm.nih.gov/pubmed/35224417 http://dx.doi.org/10.1002/rth2.12666 |
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