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COVID‐19 and venous thromboembolism: A narrative review

COVID‐19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) is associated with coagulopathy through numerous mechanisms. The reported incidence of venous thromboembolism (VTE) in hospitalized patients with COVID‐19 has varied widely, and several meta‐analyses have been performed to asses...

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Autores principales: Angelini, Dana E., Kaatz, Scott, Rosovsky, Rachel P., Zon, Rebecca L., Pillai, Shreejith, Robertson, William E., Elavalakanar, Pavania, Patell, Rushad, Khorana, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847419/
https://www.ncbi.nlm.nih.gov/pubmed/35224417
http://dx.doi.org/10.1002/rth2.12666
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author Angelini, Dana E.
Kaatz, Scott
Rosovsky, Rachel P.
Zon, Rebecca L.
Pillai, Shreejith
Robertson, William E.
Elavalakanar, Pavania
Patell, Rushad
Khorana, Alok
author_facet Angelini, Dana E.
Kaatz, Scott
Rosovsky, Rachel P.
Zon, Rebecca L.
Pillai, Shreejith
Robertson, William E.
Elavalakanar, Pavania
Patell, Rushad
Khorana, Alok
author_sort Angelini, Dana E.
collection PubMed
description COVID‐19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) is associated with coagulopathy through numerous mechanisms. The reported incidence of venous thromboembolism (VTE) in hospitalized patients with COVID‐19 has varied widely, and several meta‐analyses have been performed to assess the overall prevalence of VTE. The novelty of this coronavirus strain along with its unique mechanisms for microvascular and macrovascular thrombosis has led to uncertainty as to how to diagnose, prevent, and treat thrombosis in patients affected by this virus. This review discusses the epidemiology and pathophysiology of thrombosis in the setting of SARS‐CoV‐2 infection along with an updated review on the preventative and treatment strategies for VTE associated with SARS‐CoV‐2 infection.
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spelling pubmed-88474192022-02-25 COVID‐19 and venous thromboembolism: A narrative review Angelini, Dana E. Kaatz, Scott Rosovsky, Rachel P. Zon, Rebecca L. Pillai, Shreejith Robertson, William E. Elavalakanar, Pavania Patell, Rushad Khorana, Alok Res Pract Thromb Haemost Review Article COVID‐19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) is associated with coagulopathy through numerous mechanisms. The reported incidence of venous thromboembolism (VTE) in hospitalized patients with COVID‐19 has varied widely, and several meta‐analyses have been performed to assess the overall prevalence of VTE. The novelty of this coronavirus strain along with its unique mechanisms for microvascular and macrovascular thrombosis has led to uncertainty as to how to diagnose, prevent, and treat thrombosis in patients affected by this virus. This review discusses the epidemiology and pathophysiology of thrombosis in the setting of SARS‐CoV‐2 infection along with an updated review on the preventative and treatment strategies for VTE associated with SARS‐CoV‐2 infection. John Wiley and Sons Inc. 2022-02-15 /pmc/articles/PMC8847419/ /pubmed/35224417 http://dx.doi.org/10.1002/rth2.12666 Text en © 2022 The Authors. Research and Practice in Thrombosis and Haemostasis published by Wiley Periodicals LLC on behalf of International Society on Thrombosis and Haemostasis (ISTH). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review Article
Angelini, Dana E.
Kaatz, Scott
Rosovsky, Rachel P.
Zon, Rebecca L.
Pillai, Shreejith
Robertson, William E.
Elavalakanar, Pavania
Patell, Rushad
Khorana, Alok
COVID‐19 and venous thromboembolism: A narrative review
title COVID‐19 and venous thromboembolism: A narrative review
title_full COVID‐19 and venous thromboembolism: A narrative review
title_fullStr COVID‐19 and venous thromboembolism: A narrative review
title_full_unstemmed COVID‐19 and venous thromboembolism: A narrative review
title_short COVID‐19 and venous thromboembolism: A narrative review
title_sort covid‐19 and venous thromboembolism: a narrative review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847419/
https://www.ncbi.nlm.nih.gov/pubmed/35224417
http://dx.doi.org/10.1002/rth2.12666
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