TLR4 is a regulator of trained immunity in a murine model of Duchenne muscular dystrophy

Dysregulation of the balance between pro-inflammatory and anti-inflammatory macrophages has a key function in the pathogenesis of Duchenne muscular dystrophy (DMD), a fatal genetic disease. We postulate that an evolutionarily ancient protective mechanism against infection, known as trained immunity,...

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Detalles Bibliográficos
Autores principales: Bhattarai, Salyan, Li, Qian, Ding, Jun, Liang, Feng, Gusev, Ekaterina, Lapohos, Orsolya, Fonseca, Gregory J., Kaufmann, Eva, Divangahi, Maziar, Petrof, Basil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847425/
https://www.ncbi.nlm.nih.gov/pubmed/35169163
http://dx.doi.org/10.1038/s41467-022-28531-1

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