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COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men

With the implementation of COVID-19 vaccine up-take, doubts regarding the impact of immunization on future fertility have begun to emerge. We have examined vaccine safety on male reproductive health. We set up a multicentre (three infertility centers), retrospective study in order to assess semen pa...

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Autores principales: Reschini, Marco, Pagliardini, Luca, Boeri, Luca, Piazzini, Francesca, Bandini, Veronica, Fornelli, Gianfranco, Dolci, Carolina, Cermisoni, Greta Chiara, Viganò, Paola, Somigliana, Edgardo, Coccia, Maria Elisabetta, Papaleo, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847439/
https://www.ncbi.nlm.nih.gov/pubmed/35186854
http://dx.doi.org/10.3389/fpubh.2022.839967
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author Reschini, Marco
Pagliardini, Luca
Boeri, Luca
Piazzini, Francesca
Bandini, Veronica
Fornelli, Gianfranco
Dolci, Carolina
Cermisoni, Greta Chiara
Viganò, Paola
Somigliana, Edgardo
Coccia, Maria Elisabetta
Papaleo, Enrico
author_facet Reschini, Marco
Pagliardini, Luca
Boeri, Luca
Piazzini, Francesca
Bandini, Veronica
Fornelli, Gianfranco
Dolci, Carolina
Cermisoni, Greta Chiara
Viganò, Paola
Somigliana, Edgardo
Coccia, Maria Elisabetta
Papaleo, Enrico
author_sort Reschini, Marco
collection PubMed
description With the implementation of COVID-19 vaccine up-take, doubts regarding the impact of immunization on future fertility have begun to emerge. We have examined vaccine safety on male reproductive health. We set up a multicentre (three infertility centers), retrospective study in order to assess semen parameters and fertilization rate of one hundred-six men in a pairwise comparison between the first and second assisted reproduction technology (ART) attempt, performed respectively before and after COVID-19 vaccination. Median time (range) between the first vaccine dose and the second ART cycle was 75 days (39–112). Semen parameters did not change before and after the exposure. Fertilization rate was also similar before and after vaccination. Twenty-five patients (24%) were oligozoospermic before the vaccination while 26 (25%) after the exposure (P = 0.87). Severe asthenozoospermia were present in 11 patients before as well as after the exposure. No difference was observed even after considering different types of vaccines (mRNA or viral vector). COVID-19 vaccination did not affect sperm quality and fertilization capacity of men undergoing ART treatments and should be considered safe for men's reproductive health.
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spelling pubmed-88474392022-02-17 COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men Reschini, Marco Pagliardini, Luca Boeri, Luca Piazzini, Francesca Bandini, Veronica Fornelli, Gianfranco Dolci, Carolina Cermisoni, Greta Chiara Viganò, Paola Somigliana, Edgardo Coccia, Maria Elisabetta Papaleo, Enrico Front Public Health Public Health With the implementation of COVID-19 vaccine up-take, doubts regarding the impact of immunization on future fertility have begun to emerge. We have examined vaccine safety on male reproductive health. We set up a multicentre (three infertility centers), retrospective study in order to assess semen parameters and fertilization rate of one hundred-six men in a pairwise comparison between the first and second assisted reproduction technology (ART) attempt, performed respectively before and after COVID-19 vaccination. Median time (range) between the first vaccine dose and the second ART cycle was 75 days (39–112). Semen parameters did not change before and after the exposure. Fertilization rate was also similar before and after vaccination. Twenty-five patients (24%) were oligozoospermic before the vaccination while 26 (25%) after the exposure (P = 0.87). Severe asthenozoospermia were present in 11 patients before as well as after the exposure. No difference was observed even after considering different types of vaccines (mRNA or viral vector). COVID-19 vaccination did not affect sperm quality and fertilization capacity of men undergoing ART treatments and should be considered safe for men's reproductive health. Frontiers Media S.A. 2022-02-02 /pmc/articles/PMC8847439/ /pubmed/35186854 http://dx.doi.org/10.3389/fpubh.2022.839967 Text en Copyright © 2022 Reschini, Pagliardini, Boeri, Piazzini, Bandini, Fornelli, Dolci, Cermisoni, Viganò, Somigliana, Coccia and Papaleo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Reschini, Marco
Pagliardini, Luca
Boeri, Luca
Piazzini, Francesca
Bandini, Veronica
Fornelli, Gianfranco
Dolci, Carolina
Cermisoni, Greta Chiara
Viganò, Paola
Somigliana, Edgardo
Coccia, Maria Elisabetta
Papaleo, Enrico
COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men
title COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men
title_full COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men
title_fullStr COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men
title_full_unstemmed COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men
title_short COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men
title_sort covid-19 vaccination does not affect reproductive health parameters in men
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847439/
https://www.ncbi.nlm.nih.gov/pubmed/35186854
http://dx.doi.org/10.3389/fpubh.2022.839967
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