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Mitochondrial DNA diversity of the Sardinian local cattle stock
The aim of this research was to characterize the genetic diversity of the Sarda (Sa, n = 131), Sardo Bruna (SB, n = 44) and Sardo Modicana (SM, n = 26) cattle breeds, reared in the island of Sardinia (Italy). A portion of the mitochondrial DNA hypervariable region was sequenced, in order to identify...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847569/ https://www.ncbi.nlm.nih.gov/pubmed/35169207 http://dx.doi.org/10.1038/s41598-022-06420-3 |
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author | Petretto, Elena Dettori, Maria Luisa Pazzola, Michele Manca, Fabio Amills, Marcel Vacca, Giuseppe Massimo |
author_facet | Petretto, Elena Dettori, Maria Luisa Pazzola, Michele Manca, Fabio Amills, Marcel Vacca, Giuseppe Massimo |
author_sort | Petretto, Elena |
collection | PubMed |
description | The aim of this research was to characterize the genetic diversity of the Sarda (Sa, n = 131), Sardo Bruna (SB, n = 44) and Sardo Modicana (SM, n = 26) cattle breeds, reared in the island of Sardinia (Italy). A portion of the mitochondrial DNA hypervariable region was sequenced, in order to identify a potential signature of African introgression. The F(ST) coefficients among populations ranged between 0.056 for Sa vs SB and 0.167 for SB vs SM. AMOVA analysis indicated there was a significant differentiation of the three breeds, although most of diversity was gathered at the within-breed level. The Median Joining Network of the Sardinian sequences showed a potential founder effect signature. A MJ network including Sardinian cattle plus African, Italian, Iberian and Asian sequences, revealed the presence of haplogroup T3, already detected in Sa cattle, and the presence of Hg T1 and Hg T1′2′3, in Sa and SB. The presence of a private haplotype belonging to haplogroup T1, which is characteristic of African taurine breeds, may be due to the introgression of Sardinian breeds with African cattle, either directly (most probable source: North African cattle) or indirectly (through a Mediterranean intermediary already introgressed with African blood). |
format | Online Article Text |
id | pubmed-8847569 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-88475692022-02-17 Mitochondrial DNA diversity of the Sardinian local cattle stock Petretto, Elena Dettori, Maria Luisa Pazzola, Michele Manca, Fabio Amills, Marcel Vacca, Giuseppe Massimo Sci Rep Article The aim of this research was to characterize the genetic diversity of the Sarda (Sa, n = 131), Sardo Bruna (SB, n = 44) and Sardo Modicana (SM, n = 26) cattle breeds, reared in the island of Sardinia (Italy). A portion of the mitochondrial DNA hypervariable region was sequenced, in order to identify a potential signature of African introgression. The F(ST) coefficients among populations ranged between 0.056 for Sa vs SB and 0.167 for SB vs SM. AMOVA analysis indicated there was a significant differentiation of the three breeds, although most of diversity was gathered at the within-breed level. The Median Joining Network of the Sardinian sequences showed a potential founder effect signature. A MJ network including Sardinian cattle plus African, Italian, Iberian and Asian sequences, revealed the presence of haplogroup T3, already detected in Sa cattle, and the presence of Hg T1 and Hg T1′2′3, in Sa and SB. The presence of a private haplotype belonging to haplogroup T1, which is characteristic of African taurine breeds, may be due to the introgression of Sardinian breeds with African cattle, either directly (most probable source: North African cattle) or indirectly (through a Mediterranean intermediary already introgressed with African blood). Nature Publishing Group UK 2022-02-15 /pmc/articles/PMC8847569/ /pubmed/35169207 http://dx.doi.org/10.1038/s41598-022-06420-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Petretto, Elena Dettori, Maria Luisa Pazzola, Michele Manca, Fabio Amills, Marcel Vacca, Giuseppe Massimo Mitochondrial DNA diversity of the Sardinian local cattle stock |
title | Mitochondrial DNA diversity of the Sardinian local cattle stock |
title_full | Mitochondrial DNA diversity of the Sardinian local cattle stock |
title_fullStr | Mitochondrial DNA diversity of the Sardinian local cattle stock |
title_full_unstemmed | Mitochondrial DNA diversity of the Sardinian local cattle stock |
title_short | Mitochondrial DNA diversity of the Sardinian local cattle stock |
title_sort | mitochondrial dna diversity of the sardinian local cattle stock |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847569/ https://www.ncbi.nlm.nih.gov/pubmed/35169207 http://dx.doi.org/10.1038/s41598-022-06420-3 |
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