Calcium Signaling Is Impaired in PTEN-Deficient T Cell Acute Lymphoblastic Leukemia

PTEN (Phosphatase and TENsin homolog) is a well-known tumor suppressor involved in numerous types of cancer, including T-cell acute lymphoblastic leukemia (T-ALL). In human, loss-of-function mutations of PTEN are correlated to mature T-ALL expressing a T-cell receptor (TCR) at their cell surface. In...

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Detalles Bibliográficos
Autores principales: Pankaew, Saran, Potier, Delphine, Grosjean, Clémence, Nozais, Mathis, Quessada, Julie, Loosveld, Marie, Remy, Élisabeth, Payet-Bornet, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847596/
https://www.ncbi.nlm.nih.gov/pubmed/35185889
http://dx.doi.org/10.3389/fimmu.2022.797244

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