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Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction

BACKGROUND: The superior therapeutic benefit of clozapine is often associated with metabolic disruptions as obesity, insulin resistance, tachycardia, higher blood pressure, and even hypertension. AIMS: These adverse vascular/ metabolic events under clozapine are similar to those caused by polycyclic...

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Detalles Bibliográficos
Autores principales: Fehsel, K, Schwanke, K, Kappel, BA, Fahimi, E, Meisenzahl-Lechner, E, Esser, C, Hemmrich, K, Haarmann-Stemmann, T, Kojda, G, Lange-Asschenfeldt, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847763/
https://www.ncbi.nlm.nih.gov/pubmed/34979820
http://dx.doi.org/10.1177/02698811211055811