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Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction
BACKGROUND: The superior therapeutic benefit of clozapine is often associated with metabolic disruptions as obesity, insulin resistance, tachycardia, higher blood pressure, and even hypertension. AIMS: These adverse vascular/ metabolic events under clozapine are similar to those caused by polycyclic...
Autores principales: | Fehsel, K, Schwanke, K, Kappel, BA, Fahimi, E, Meisenzahl-Lechner, E, Esser, C, Hemmrich, K, Haarmann-Stemmann, T, Kojda, G, Lange-Asschenfeldt, C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847763/ https://www.ncbi.nlm.nih.gov/pubmed/34979820 http://dx.doi.org/10.1177/02698811211055811 |
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