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Choosing and changing the analysis scale in non-inferiority trials with a binary outcome
BACKGROUND: The size of the margin strongly influences the required sample size in non-inferiority and equivalence trials. What is sometimes ignored, however, is that for trials with binary outcomes, the scale of the margin – risk difference, risk ratio or odds ratio – also has a large impact on pow...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847766/ https://www.ncbi.nlm.nih.gov/pubmed/34693789 http://dx.doi.org/10.1177/17407745211053790 |