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Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation

Catabolite control protein A (CcpA) of the human pathogen Staphylococcus aureus is an essential DNA regulator for carbon catabolite repression and virulence, which facilitates bacterial survival and adaptation to a changing environment. Here, we report that copper (II) signaling mediates the DNA-bin...

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Detalles Bibliográficos
Autores principales: Liao, Xiangwen, Li, Huinan, Guo, Yu, Yang, Fang, Chen, Yushou, He, Xiaojun, Li, Hongyan, Xia, Wei, Mao, Zong-Wan, Sun, Hongzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847796/
https://www.ncbi.nlm.nih.gov/pubmed/35032550
http://dx.doi.org/10.1016/j.jbc.2022.101587