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Novel functional polymorphism on PADI-4 gene and its association with arthritis onset

BACKGROUND: Citrullinated proteins formed by peptidyl arginine deiminases (PADIs) deimination of arginine residues in proteins are of particular interest in arthritis pathogenesis. Polymorphisms on the PADI-4 gene lead to the malfunctioning of PADIs leading to the onset of arthritis. OBJECTIVE: The ...

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Detalles Bibliográficos
Autores principales: Mukhtar, Maryam, Sheikh, Nadeem, Batool, Andleeb, Khawar, Muhammad Babar, Fatima, Naz, Mehmood, Rabia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847927/
https://www.ncbi.nlm.nih.gov/pubmed/35197789
http://dx.doi.org/10.1016/j.sjbs.2021.09.037