Cargando…

SENP3 loss promotes M2 macrophage polarization and breast cancer progression

Tumor‐associated macrophages (TAM) play a crucial role in promoting cancer progression. Upon cytokine stimulation, TAM preferentially polarize to the anti‐inflammatory and pro‐tumor M2 subtype. The mechanism underlying such preferential polarization remains elusive. Here, we report that macrophage‐s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Ming, Bian, Qi, Lao, Yimin, Yi, Jing, Sun, Xueqing, Sun, Xuxu, Yang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847990/ https://www.ncbi.nlm.nih.gov/pubmed/33932085 http://dx.doi.org/10.1002/1878-0261.12967

Ejemplares similares

DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages
por: Lao, Yimin, et al.
Publicado: (2018)

SENP3 in monocytes/macrophages up‐regulates tissue factor and mediates lipopolysaccharide‐induced acute lung injury by enhancing JNK phosphorylation
por: Chen, Xuelian, et al.
Publicado: (2020)

Assessment of SENP3-interacting proteins in hepatocytes treated with diethylnitrosamine by BioID assay
por: Chen, Fei, et al.
Publicado: (2021)

SENP3 deletion promotes M2 macrophage polarization and accelerates wound healing through smad6/IκB/p65 signaling pathway
por: Ma, Yiwen, et al.
Publicado: (2023)

IDO1 Promotes the Progression of NSCLC by Regulating the Polarization of M2 Macrophages
por: Chen, Xiao, et al.
Publicado: (2023)

SENP3 promotes tumor progression and is a novel prognostic biomarker in triple-negative breast cancer
por: Zhu, Youzhi, et al.
Publicado: (2023)

Association of SENPs single-nucleotide polymorphism and breast cancer in Chinese population
por: Cai, Jiaqin, et al.
Publicado: (2019)

Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage
por: Bao, Ximing, et al.
Publicado: (2023)

Genetic Polymorphism of SUMO-Specific Cysteine Proteases − SENP1 and SENP2 in Breast Cancer
por: Mirecka, Alicja, et al.
Publicado: (2016)

SENP3 facilitates M1 macrophage polarization via the HIF-1α/PKM2 axis in lipopolysaccharide-induced acute lung injury
por: He, Shuangjun, et al.
Publicado: (2023)

Discovery of a Dual SENP1 and SENP2 Inhibitor
por: Brand, Michael, et al.
Publicado: (2022)

Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90
por: Yan, Shan, et al.
Publicado: (2010)

SENP1 and SENP2 regulate SUMOylation of amyloid precursor protein
por: Maruyama, Takuma, et al.
Publicado: (2018)

SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis
por: Cubeñas-Potts, Caelin, et al.
Publicado: (2013)

BST2 induced macrophage M2 polarization to promote the progression of colorectal cancer
por: He, Xuefeng, et al.
Publicado: (2023)

NMAAP1 Expressed in BCG-Activated Macrophage Promotes M1 Macrophage Polarization
por: Liu, Qihui, et al.
Publicado: (2015)

Tumor-associated macrophage polarization promotes the progression of esophageal carcinoma
por: Yuan, Xin, et al.
Publicado: (2020)

Musashi-1 Regulates MIF1-Mediated M2 Macrophage Polarization in Promoting Glioblastoma Progression
por: Yang, Yi-Ping, et al.
Publicado: (2021)

Etanercept alleviates psoriasis by reducing the Th17/Treg ratio and promoting M2 polarization of macrophages
por: Li, Xiaoqing, et al.
Publicado: (2022)

Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of β-catenin and regulation of its stability
por: Cai, Zhaohua, et al.
Publicado: (2021)

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
por: Yu, Xiaoyan, et al.
Publicado: (2018)

Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo
por: Zhang, Michael, et al.
Publicado: (2016)

The imbalance of liver resident macrophages polarization promotes chronic autoimmune hepatitis development in mice
por: Chi, Gang, et al.
Publicado: (2023)

De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells
por: Ren, Yan-hua, et al.
Publicado: (2014)

Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2
por: Chow, Kin-Hoe, et al.
Publicado: (2012)

Adrenergic receptor β2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment
por: Qin, Jun-fang, et al.
Publicado: (2015)

Weak UVB Irradiation Promotes Macrophage M2 Polarization and Stabilizes Atherosclerosis
por: Li, Xin-Yun, et al.
Publicado: (2021)

Loss of LXN promotes macrophage M2 polarization and PD-L2 expression contributing cancer immune-escape in mice
por: Li, Yaping, et al.
Publicado: (2022)

AhR activation attenuates calcium oxalate nephrocalcinosis by diminishing M1 macrophage polarization and promoting M2 macrophage polarization
por: Yang, Xiaoqi, et al.
Publicado: (2020)

TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity
por: Li, Yun-Yi, et al.
Publicado: (2022)

Lessons on Life from SENP2
por: Sedwick, Caitlin
Publicado: (2008)

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
por: Cui, Chun-Ping, et al.
Publicado: (2017)

Hydrogen Promotes the M1 Macrophage Conversion During the Polarization of Macrophages in Necrotizing Enterocolitis
por: Yu, Shenghua, et al.
Publicado: (2021)

CD47 Blockade Inhibits Tumor Progression through Promoting Phagocytosis of Tumor Cells by M2 Polarized Macrophages in Endometrial Cancer
por: Gu, Shenglan, et al.
Publicado: (2018)

The SUMO Protease SENP3 Orchestrates G2-M Transition and Spindle Assembly in Mouse Oocytes
por: Huang, Chun-Jie, et al.
Publicado: (2015)

Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression
por: Li, Ming, et al.
Publicado: (2022)

Inhibition of SENP5 suppresses cell growth and promotes apoptosis in osteosarcoma cells
por: WANG, KUN, et al.
Publicado: (2014)

Zinc deficiency induces abnormal development of the myocardium by promoting SENP5 overexpression
por: Zhang, Xiaoyu, et al.
Publicado: (2020)

SENP2 Promotes VSMC Phenotypic Switching via Myocardin De-SUMOylation
por: Liang, Min, et al.
Publicado: (2022)

Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss
por: Wang, Liling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_37j4g1c0ocn2s0fj0kca6451rb